ID H2U6B4_TAKRU Unreviewed; 578 AA.
AC H2U6B4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000032480.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000032480.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000032480.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSTRUT00000032604.3; ENSTRUP00000032480.3; ENSTRUG00000021854.2.
DR Ensembl; ENSTRUT00000088692.1; ENSTRUP00000057727.1; ENSTRUG00000021854.2.
DR eggNOG; ENOG502S65W; Eukaryota.
DR GeneTree; ENSGT00940000176205; -.
DR HOGENOM; CLU_049836_0_0_1; -.
DR Proteomes; UP000005226; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11481:SF64; CD166 ANTIGEN-LIKE-RELATED; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13895; Ig_2; 2.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 464..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..85
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 95..179
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 184..268
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 280..355
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 370..450
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 413..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 578 AA; 65545 MW; 03B6D320F8478FEC CRC64;
MPKVTLTQDP DYKVIFPGES VVFSCHINNS YGWEYIWLKD MNSLPHTDKR LSISPRDSSD
QGSYECQAKR GTGHPFYTDK SRTVNIKVEE NKPQPLMTQQ PDVEKVYIGE PVSFKCEIKD
SAGWEYVWFK DGKELPLNTN VLDIPHASLS DSGTYECKGI RNKTKYDSKN SHRRQVLISE
IPSPKVENIT QWLHVFPTES LRLSCEMDGS SDWMFSWHKD GQEVHAGQDV SFDKDATVLS
INSASASHRG RYSCSGKHKQ RTVSSNVSSG IQLDVYDTKP RVQLSQSPEH TLMHTEDSVT
FLCHINISTG WEFLWFKDDR PLTVPGNNLT LSSMSVKNTG LYKCQTRRGT SLIFSSDPSP
TIYLTVEERP KAKVILLTGW SQVFSTDSLQ LSCRLQNSQE RWNYTWYRDG QKLENPPSPT
YRVTPQDDPE QSQYSCQGIR NGTLSYSRIS DRFWTKNLLL KRRLLLSIAG CIVFGICMIC
IGSIVLRMCR KKAQEDYKPE EADLFLRMDA LKDSDDGPPL LVQYVTESAL NSLSKEEGEN
GTVISESPLP PVQEEPATTT ESPEAMQNNN SGLISFKQ
//
