GenomeNet

Database: UniProt
Entry: H2U9D9_TAKRU
LinkDB: H2U9D9_TAKRU
Original site: H2U9D9_TAKRU 
ID   H2U9D9_TAKRU            Unreviewed;       833 AA.
AC   H2U9D9;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   10-OCT-2018, entry version 38.
DE   SubName: Full=Transient receptor potential cation channel subfamily C member 6 {ECO:0000313|Ensembl:ENSTRUP00000033555};
GN   Name=TRPC6 (1 of many) {ECO:0000313|Ensembl:ENSTRUP00000033555};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000033555, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000033555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
RA   Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu
RT   facilitates insights into distinct features of genome evolution in
RT   teleosts and mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000033555}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS01006510}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   Ensembl; ENSTRUT00000033681; ENSTRUP00000033555; ENSTRUG00000013189.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   GeneTree; ENSGT00760000119180; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005462; TRPC6_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 2.
DR   PANTHER; PTHR10117:SF7; PTHR10117:SF7; 2.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Ion channel {ECO:0000256|SAAS:SAAS00790162};
KW   Ion transport {ECO:0000256|SAAS:SAAS00790154};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00788392}.
FT   TRANSMEM    347    367       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    379    402       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    468    492       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    572    596       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    645    665       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       46    127       ANK_REP_REGION. {ECO:0000259|Pfam:
FT                                PF12796}.
FT   DOMAIN      192    254       TRP_2. {ECO:0000259|Pfam:PF08344}.
FT   DOMAIN      420    675       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   833 AA;  94815 MW;  DA1D052B8A8A1AE7 CRC64;
     EEETNSIRGK TVMAAKCHIQ AFRGAGYLSR TQSARYLLKT EDHFLDAAEN GNVPKVVQML
     AELPDLNVNY VNCKGQNALQ LAVANERLEV TKRLLKKKDL TRIGDALLLA ISKGYVRIVE
     ALLSHQAFLD GQRLSDCLSQ SDDDFFTFDE DGTRFSRDIT PIILASQCHQ YEMVHILLMK
     GARIERPHDY FCQCRACSDE QSRDSFSHSQ SRINAYKGLA SPAYLCLSSE DPVMEALELG
     NELSILANTE KEFKNDYTNL STQCKDFVVG LLDLCRNTEE VKAILNGDAE SCQNADTSCR
     QNLYRLKLAI RYEVKKFVAH PNCQQQLLSI WYEDLSGVRQ QNTAVKILLV LGVAAGLPVL
     AFIYWLAPSS KLGKLMHGPF LKFVAHAASF IIFLCLLVLN GIDRFGGTSL LPNMTTRDHP
     LQLFRMKTTP FTWMEILIIS WVTGNIWKGC KEIWVQDIGE YMSEPWNLLD FSILATFMAS
     FIARLMAFWH AYSAQCYIDK HYSDLANMNL PFEIQYFQLA RIDWLPSDPQ LISEGLYAVA
     VVLSFSRIAY ILPANESFGP LQISLGRTVK DIFKFMVIFT TVFVAFMVGM FSLYSYYLGV
     KYNNAFTTIE ESFKTLFWAI FGLSEVKSVV INIDHKFIEN IGYVLYGVYN IIMVIVLLNM
     LIAMFNSSFQ EIEGDADVEW KFARAKLWFA YFEHCSTLPV PFNLIPTPNS VLSLWLGIRD
     SLWNRPQSNS QHSSNDVLEL NKLNHKEDQR TEATLGPTHY QKIMNRLVKR YILKAQSDKE
     NSQVNEGELK EIKQDISSLH YELAERGSSD AEKLANLIRH LDQVMQKKGA QGP
//
DBGET integrated database retrieval system