ID H2UBH0_TAKRU Unreviewed; 453 AA.
AC H2UBH0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Elongation factor 1-delta {ECO:0000256|ARBA:ARBA00039378};
GN Name=LOC101071471 {ECO:0000313|Ensembl:ENSTRUP00000034288.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000034288.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000034288.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000034288.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the EF-1-beta/EF-1-delta family.
CC {ECO:0000256|ARBA:ARBA00007411}.
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DR AlphaFoldDB; H2UBH0; -.
DR STRING; 31033.ENSTRUP00000072005; -.
DR Ensembl; ENSTRUT00000034414.3; ENSTRUP00000034288.3; ENSTRUG00000013449.3.
DR eggNOG; KOG1668; Eukaryota.
DR GeneTree; ENSGT00950000183014; -.
DR HOGENOM; CLU_047136_0_0_1; -.
DR TreeFam; TF313134; -.
DR Proteomes; UP000005226; Chromosome 22.
DR GO; GO:0005853; C:eukaryotic translation elongation factor 1 complex; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd00292; EF1B; 1.
DR Gene3D; 3.30.70.60; -; 1.
DR InterPro; IPR036219; eEF-1beta-like_sf.
DR InterPro; IPR018940; EF-1_beta_acid_region_euk.
DR InterPro; IPR049720; EF1B_bsu/dsu.
DR InterPro; IPR014038; EF1B_bsu/dsu_GNE.
DR InterPro; IPR014717; Transl_elong_EF1B/ribsomal_bS6.
DR InterPro; IPR001326; Transl_elong_EF1B_B/D_CS.
DR PANTHER; PTHR11595; EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER; 1.
DR PANTHER; PTHR11595:SF26; ELONGATION FACTOR 1-DELTA; 1.
DR Pfam; PF10587; EF-1_beta_acid; 1.
DR Pfam; PF00736; EF1_GNE; 1.
DR SMART; SM01182; EF-1_beta_acid; 1.
DR SMART; SM00888; EF1_GNE; 1.
DR SUPFAM; SSF54984; eEF-1beta-like; 1.
DR PROSITE; PS00824; EF1BD_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Elongation factor {ECO:0000256|ARBA:ARBA00022768};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 340..365
FT /note="Elongation factor 1 beta central acidic region
FT eukaryote"
FT /evidence="ECO:0000259|SMART:SM01182"
FT DOMAIN 374..451
FT /note="Translation elongation factor EF1B beta/delta
FT subunit guanine nucleotide exchange"
FT /evidence="ECO:0000259|SMART:SM00888"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 272..306
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 17..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 50253 MW; F2E0177EE5883A25 CRC64;
MGDPLPNLPH ALPLGDLSLS SNPSLERSKN PSLERSIIKS KAQFGRVRRH SRLSQSESSG
AEEEWLSPSA DATSSYARSP FLQCIPAQGL MYHRSAFEQA ESTDQCWARS NSNEVLSSSP
RSPNTRSYFG SQSGLSRSLH QNKGHPAAPM KSSGTHHHQS IRGRNRTSSE TEPRAKSSKT
PTQRKRGLSE TESWTLRDNI NMSGLQCLAS ENVWFDKHRF DEAEKRFYEG ANGPAPQQQQ
VKTATHQAKG RHQKRQHRNS SSHGDQELVS RMKSLELENQ SLHKVVENMK AALQKLESRV
AVLEKAPTKA AVPCAKAAPV QAAPVKQVAN GDDDDDDLDL FGSDEEDEDT ARIKQERLDA
YAAKKSKKPA LIAKSSILLD VKPWDDETDM SMLEKCVRSV QMDGLLWGAS KLVPVGYGIK
KLQINCVVED DKVGTDILEE EITKFEDFLP ISS
//
