ID H2URQ6_TAKRU Unreviewed; 551 AA.
AC H2URQ6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Ceramide kinase {ECO:0000313|Ensembl:ENSTRUP00000039629.2};
GN Name=CERK {ECO:0000313|Ensembl:ENSTRUP00000039629.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000039629.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000039629.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000039629.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2URQ6; -.
DR STRING; 31033.ENSTRUP00000078863; -.
DR Ensembl; ENSTRUT00000039770.3; ENSTRUP00000039629.2; ENSTRUG00000015494.3.
DR eggNOG; KOG1115; Eukaryota.
DR GeneTree; ENSGT00940000156976; -.
DR TreeFam; TF314514; -.
DR Proteomes; UP000005226; Chromosome 9.
DR GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR045363; CERK_C.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF25; CERAMIDE KINASE; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF19280; CERK_C; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 131..282
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 551 AA; 62433 MW; 23A7553B0D2031DD CRC64;
MEKPNRLLLL SELRVRNTAY DVSLSRSVLT WKRRSSSPVY HPFRPSVCHN VPVSEIVAVR
EEEEENRDDG SWKKIKEREG KDCRQAFTVL YVERCQRHRW RCAEVTFACP DEALCQLWIS
SIREQLAATT SRPKHLLVYI NPYGGKRKGK HIYELKVAPL FAQAGIRTHV IVTDYANHAR
DHLKTQAELK KFDGVVCVGG DGMFSEIIHG LIWRTQADNG RNLNSPEETL LPCSLRIGII
PAGSTDCICF ATVGTNDPVT SALHIIVGDS QSMDVCSVHH NNTFLRYSVS LLGYGFYGDV
LTDSERKRWM GPARYDLSGV KMFLTHHYYE GSVSYLPARD IIGTPRDPGR CHSGCSVCQH
NGEKHSESAE RYKMDIASES ESDMEWRTIR GKFLAINAAS MSCACPRSPK GLSPAAHLAD
GTTDLILVRK CSRFDFLRHL LRHTSKDDQF DLNFVEVHRV RRFCFTPRHC QSDSDLELDL
RENGKRQIFS QICRDHPACG CTPAYSSWNC DGEILTHTAI DVRVHCQLIK LFARGIEEPT
VFEDLTNPCA I
//
