ID H2US53_TAKRU Unreviewed; 521 AA.
AC H2US53;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Solute carrier family 3 member 2 {ECO:0000313|Ensembl:ENSTRUP00000039776.3};
GN Name=slc3a2 {ECO:0000313|Ensembl:ENSTRUP00000039776.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000039776.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000039776.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000039776.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2US53; -.
DR STRING; 31033.ENSTRUP00000039776; -.
DR Ensembl; ENSTRUT00000039917.3; ENSTRUP00000039776.3; ENSTRUG00000015563.3.
DR GeneTree; ENSGT00940000156646; -.
DR HOGENOM; CLU_006462_9_0_1; -.
DR InParanoid; H2US53; -.
DR OMA; WGTAPET; -.
DR Proteomes; UP000005226; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR042280; SLC3A2.
DR InterPro; IPR031984; SLC3A2_N.
DR PANTHER; PTHR46673; 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN; 1.
DR PANTHER; PTHR46673:SF3; SOLUTE CARRIER FAMILY 3 MEMBER 2B-RELATED; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF16028; SLC3A2_N; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 135..423
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT REGION 33..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 56978 MW; 2C17D1EB9F00CF50 CRC64;
MLVLHSSVAP SKQEPASTMI EVDMKEVELS EMDPEKQPMT GDGQAAAAAE KNGSVKLKVP
EDEVAFTGLS KDELMKVAGT PGWVRTRFVL LILFWLGWIG MLAGAIVIIV QAPRCKPIPE
MNWWNEGPLY EISDTQAFSD GLKGIESKLD NINQLKVKGL VLGPLHTVQA NQPSTLDLEK
FDPRQGTNEE LLGVLEKAHR KGINVMLDLT PNYLGSSSWF NPVEKDVRKV EAAAEYWLGL
GVDGIKVSDL AIASGSAEWA KLQDVVQKNS SQDGKRRALM GVVKNVSATS ASQLLNTSGV
DLLQSDLVST NIGGSELINT MDTLNSEQRS LGWGFGEQLS KQAKTPGLIR LYHLLLFTLP
GTPIFKYGDE IGLPPGQGSE PPKMIWDLEK EPAEGEADNG TVKTETLKPG ELRNWFISLS
DLRGKERSLL HGDYYSLSSS DTSLAFLRLW DQSERYITAV NWGTAPETLA FKLATPEVKL
PETAKVKLST DDDLKEESDV SLEKLTLGAG KAVLLQFPYK G
//
