ID H2UUE3_TAKRU Unreviewed; 312 AA.
AC H2UUE3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Impact RWD domain protein {ECO:0000313|Ensembl:ENSTRUP00000040568.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000040568.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000040568.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000040568.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the IMPACT family.
CC {ECO:0000256|ARBA:ARBA00007665}.
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DR AlphaFoldDB; H2UUE3; -.
DR STRING; 31033.ENSTRUP00000082538; -.
DR Ensembl; ENSTRUT00000040710.3; ENSTRUP00000040568.2; ENSTRUG00000015867.3.
DR GeneTree; ENSGT00390000017571; -.
DR Proteomes; UP000005226; Chromosome 20.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.30; Impact, N-terminal domain; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR023582; Impact.
DR InterPro; IPR001498; Impact_N.
DR InterPro; IPR036956; Impact_N_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR020569; UPF0029_Impact_CS.
DR PANTHER; PTHR16301; IMPACT-RELATED; 1.
DR PANTHER; PTHR16301:SF20; PROTEIN IMPACT; 1.
DR Pfam; PF05773; RWD; 1.
DR Pfam; PF01205; UPF0029; 1.
DR SMART; SM00591; RWD; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50908; RWD; 1.
DR PROSITE; PS00910; UPF0029; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 15..117
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
SQ SEQUENCE 312 AA; 35754 MW; 8C005E12BD67FB58 CRC64;
MQRVSSACCL CDWTDEIEAL SSIYGEEWCV IDEAARIFCI KICNGLEKPK LTACLQIILP
HEYPSTSPPI YQINAAWLRG SERAKLANSL EDLYVENMGE SILYLWVEKV REFLVERSQM
DQPEKVNMTA EEDVEDDTQV PDIRTFSDSA EESHLYAERV NDEELPPIKH GESITDRRST
FQPHLAPVVS PRQVKMILEK LYENKKIASA THNIYAYRIY CEDKHSFLQD CEDDGETAAG
GRLLHLLQIL DVRNVMVVVS RWYGGILLGP DRFKHINNCA RNILVEEGYA ASTVRRPSEE
SRFQLLLRPS NL
//
