ID H2UUQ5_TAKRU Unreviewed; 217 AA.
AC H2UUQ5; H2UUQ6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Sorting nexin-10A {ECO:0000313|Ensembl:ENSTRUP00000040680.2};
GN Name=LOC101064034 {ECO:0000313|Ensembl:ENSTRUP00000040680.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000040680.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000040680.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000040680.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR RefSeq; XP_003969095.1; XM_003969046.2.
DR RefSeq; XP_011607391.1; XM_011609089.1.
DR RefSeq; XP_011607393.1; XM_011609091.1.
DR AlphaFoldDB; H2UUQ5; -.
DR STRING; 31033.ENSTRUP00000040680; -.
DR Ensembl; ENSTRUT00000040822.3; ENSTRUP00000040680.2; ENSTRUG00000015910.3.
DR GeneID; 101064034; -.
DR KEGG; tru:101064034; -.
DR CTD; 403027; -.
DR GeneTree; ENSGT00940000156007; -.
DR InParanoid; H2UUQ5; -.
DR OMA; TEFISIC; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000005226; Chromosome 12.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0070121; P:Kupffer's vesicle development; IEA:Ensembl.
DR GO; GO:0070986; P:left/right axis specification; IEA:Ensembl.
DR CDD; cd06898; PX_SNX10; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR043544; SNX10/11.
DR PANTHER; PTHR46209; PX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46209:SF2; SORTING NEXIN-10; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 13..130
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 180..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 217 AA; 24495 MW; 0D3A4D0E9826B280 CRC64;
MDSMLDKLAE NEFISVCVGN PRLIKKDHWR SYVDYEISLH TNSMCFRKKT STVRRRYKEF
VWLRNSLEKN ALIIEIPKLP PWNPFFSLRN MGCVLQRMEG MQEFLESVLH TPLLLSDSRL
HLFLQSDLSV MKIERCALGR SRYTVAEAIQ RTGTSCVSLL EEKRSGGFDC ESLSSGLGGS
IDGSSQGSPH SFLESSDREP ELCSGLSGSL CTLTDNS
//
