ID   H2V3H2_TAKRU            Unreviewed;       474 AA.
AC   H2V3H2;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   RecName: Full=Enhancer of mRNA-decapping protein 3 {ECO:0000256|ARBA:ARBA00015797};
DE   AltName: Full=YjeF domain-containing protein 1 {ECO:0000256|ARBA:ARBA00032192};
GN   Name=edc3 {ECO:0000313|Ensembl:ENSTRUP00000043754.1};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000043754.1, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000043754.1, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000043754.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC       {ECO:0000256|ARBA:ARBA00004201}.
CC   -!- SIMILARITY: Belongs to the EDC3 family.
CC       {ECO:0000256|ARBA:ARBA00006610}.
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DR   RefSeq; XP_003967574.1; XM_003967525.2.
DR   RefSeq; XP_011605869.1; XM_011607567.1.
DR   AlphaFoldDB; H2V3H2; -.
DR   STRING; 31033.ENSTRUP00000043754; -.
DR   Ensembl; ENSTRUT00000043900.3; ENSTRUP00000043754.1; ENSTRUG00000017078.3.
DR   GeneID; 101080130; -.
DR   KEGG; tru:101080130; -.
DR   CTD; 80153; -.
DR   eggNOG; KOG2585; Eukaryota.
DR   GeneTree; ENSGT00390000016435; -.
DR   HOGENOM; CLU_026194_0_0_1; -.
DR   InParanoid; H2V3H2; -.
DR   OMA; KNRDDEC; -.
DR   OrthoDB; 4100524at2759; -.
DR   TreeFam; TF324695; -.
DR   Proteomes; UP000005226; Chromosome 9.
DR   GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   CDD; cd01737; LSm16_N; 1.
DR   Gene3D; 2.30.30.100; -; 1.
DR   Gene3D; 3.40.50.10260; YjeF N-terminal domain; 1.
DR   InterPro; IPR025762; DFDF.
DR   InterPro; IPR019050; FDF_dom.
DR   InterPro; IPR025609; Lsm14-like_N.
DR   InterPro; IPR034107; Lsm16_N.
DR   InterPro; IPR004443; YjeF_N_dom.
DR   InterPro; IPR036652; YjeF_N_dom_sf.
DR   PANTHER; PTHR13612:SF0; ENHANCER OF MRNA-DECAPPING PROTEIN 3; 1.
DR   PANTHER; PTHR13612; UNCHARACTERIZED; 1.
DR   Pfam; PF16598; Edc3_linker; 1.
DR   Pfam; PF09532; FDF; 1.
DR   Pfam; PF12701; LSM14; 1.
DR   Pfam; PF03853; YjeF_N; 1.
DR   SMART; SM01199; FDF; 1.
DR   SMART; SM01271; LSM14; 1.
DR   SUPFAM; SSF64153; YjeF N-terminal domain-like; 1.
DR   PROSITE; PS51512; DFDF; 1.
DR   PROSITE; PS51385; YJEF_N; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   DOMAIN          157..193
FT                   /note="DFDF"
FT                   /evidence="ECO:0000259|PROSITE:PS51512"
FT   DOMAIN          249..453
FT                   /note="YjeF N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51385"
FT   REGION          71..152
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          189..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   474 AA;  52064 MW;  2963A8C5F7ADB012 CRC64;
     MASDWLGSLV SINCGPTLGV YQGEVAFVDQ SSQTISLRHP FHNGIKCPVP EVTFSAMDIK
     ELKILDIRNG STSAPAHVGS APVAVPKGDP RSMENVNSPQ HCSKSYGERH LEVPGQSKGF
     RRRHNSWSSS SRGANQATPK KNGVKNGQMK HRDDECFGDG MDEGLETDFD FEGNLALFDK
     AAVFSEIDTS ERRNGARSRG TPQEQTPSRY RHDENILEVK PIVYRQITVP QHGAKEYCTD
     SGLVVPSITY ELHKRLLSAA ERHGLSLERR LEMTGVCASQ MALTLLGGPN RFTPKNLHQH
     PTVALLCGPH VQGAQGISCG RHLANHEVEV ILFLPNFVKM LDSVTNELTL FSKTGGKQVS
     SVKDLPDTPV DLIINCLDCH ENTFLMDQPW YRAAADWANQ NRAPVLSLDP PASGQRQAVE
     AKWSLSLCLP LALAEGAGRV YLCDIGIPRQ VFQEVGIKYH SPFGCKFVIP LHSA
//