GenomeNet

Database: UniProt
Entry: H2V6V3_TAKRU
LinkDB: H2V6V3_TAKRU
Original site: H2V6V3_TAKRU 
ID   H2V6V3_TAKRU            Unreviewed;       680 AA.
AC   H2V6V3;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 2.
DT   16-JAN-2019, entry version 36.
DE   RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE            EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000044942, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000044942}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
RA   Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu
RT   facilitates insights into distinct features of genome evolution in
RT   teleosts and mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000044942}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose
CC         residues in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|RuleBase:RU000675};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|RuleBase:RU003679, ECO:0000256|SAAS:SAAS00534244}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   ProteinModelPortal; H2V6V3; -.
DR   Ensembl; ENSTRUT00000045094; ENSTRUP00000044942; ENSTRUG00000017533.
DR   GeneTree; ENSGT00390000006586; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; -; 3.
DR   InterPro; IPR026283; B-gal_1-like.
DR   InterPro; IPR025300; BetaGal_jelly_roll_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR019801; Glyco_hydro_35_CS.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421; PTHR23421; 2.
DR   Pfam; PF13364; BetaGal_dom4_5; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PIRSF; PIRSF006336; B-gal; 2.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Glycosidase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108888};
KW   Hydrolase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108869};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    680       Beta-galactosidase. {ECO:0000256|SAM:
FT                                SignalP}.
FT                                /FTId=PRO_5017408528.
FT   DOMAIN       33    348       Glyco_hydro_35. {ECO:0000259|Pfam:
FT                                PF01301}.
FT   DOMAIN      571    639       BetaGal_dom4_5. {ECO:0000259|Pfam:
FT                                PF13364}.
FT   ACT_SITE    180    180       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR006336-1}.
FT   ACT_SITE    260    260       Nucleophile. {ECO:0000256|PIRSR:
FT                                PIRSR006336-1}.
SQ   SEQUENCE   680 AA;  76195 MW;  4B4214011146E05C CRC64;
     MMGPLRFALV LLLFGRSLAA SRSFSVDYEN DCFRKDGERF RYISGSIHYS RIPRVYWKDR
     LMKMYMAGLN AVQLYIPWNY HEESPGLYNF SGNRDIQYFL QLTNDIGLLA ILRPGPYICA
     EWDMGGLPAW LLQKKDIVLR SSDPDYIAAV DKWMGKILPM IKPYLYQNGG PIITVQVENE
     YGSYFACDYN YLRHLAKLFR SHLGNEVVLF TTDGAGTGYL KCGAMQGLYA TVDFGPGSNV
     TAAFEAQRHA EPRGPLVNSE FYTGWLDHWG SPHSVVPSIA VTKSLNEMLA VGANVNMYMF
     IGGTNFGYWN GANAPYSPQP TSYDYDAPLT EAGDLTDKYF AIRNVIRMVR LAWQKKGFNI
     IIFIRLLLSW KCNFLFLFSF SLKYRNIPEG PIPPTTPKYA YGRVAMKKLQ TIFEALDILA
     FSGPVKSTYP KTFLELNQVF GYVLYRTSLP ADCSRPTPLS SPLNGVHDRA YVSVDGVTVG
     ILERNNGITI NVTGKVGSQL DILVENMGRI NYGKDINDFK GLVTNLTLGN DTLSGWTMFS
     LSIDEVVSQG LLVGTKAPQA PQPADISLPT FYQGSFVIPD GIPDLPQDTY VKLPKWRKGQ
     VWINGFNVGR YWPARGPQVT LFVPANILST AGPNNVTVLE LQGAPCSSCY VEFTASPLLN
     ATLQLDYKQA RRLFYKEDLL
//
DBGET integrated database retrieval system