ID H2XKA0_CIOIN Unreviewed; 1174 AA.
AC H2XKA0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=C-type lectin domain-containing protein {ECO:0000259|PROSITE:PS50041};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000030082.1, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000030082.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2XKA0; -.
DR Ensembl; ENSCINT00000034885.1; ENSCINP00000030082.1; ENSCING00000021453.1.
DR GeneTree; ENSGT01100000263568; -.
DR HOGENOM; CLU_002069_2_0_1; -.
DR InParanoid; H2XKA0; -.
DR OMA; TGIIWLF; -.
DR TreeFam; TF316663; -.
DR Proteomes; UP000008144; Unplaced.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd00037; CLECT; 6.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 8.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR PANTHER; PTHR22803:SF124; C-TYPE LECTIN DOMAIN FAMILY 19 MEMBER A-RELATED; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00059; Lectin_C; 8.
DR PRINTS; PR01504; PNCREATITSAP.
DR SMART; SM00034; CLECT; 8.
DR SUPFAM; SSF56436; C-type lectin-like; 8.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 4.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 8.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT DOMAIN 1..117
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 146..265
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 288..414
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 444..569
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 601..719
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 746..873
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 900..1012
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1058..1171
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
SQ SEQUENCE 1174 AA; 131391 MW; B5373002D6B510FA CRC64;
WADARLHCQS EGGDLVSINS PEEQGFIEFH VAYLNVWAVW TGGLDSYNGP DFFPDVIDAF
DGGWRWSDGT PFNFVNWVDH PPGEPNNESD EDCMEIRSDT GLWNDVPCGG YYGYICERPD
PAHINPYLTT SETGDHLGCP SGWFGWKNWC YYLPRKNHLV DYSEATQRCQ SYGAELVSVL
DQGEQDFIIN TIFFDWASAE DVWIGLNDFE TSNYFKWSDG STVTYTNWNF NEPGGDGSGH
CTKMYKFSGF WNNKDCSKEL NYMCKMDKLP VNQAQQAVDG CPSGWQGNEA SCYLFDITPS
VWVNAEDYCS DVGGHLVTIN NYFEQMYVTS QAAQTSHPDD GENFLIGLAA YLDSSGGLTY
KWASGEPVTF TAWDKDEPGR EDGMVGCITL DKDTGFWSQS RPVGCGSPGY RICEIPRTGY
TTPMVPTPPS PNGNCPDGWY GWSNATFCYQ IYINEMTDPT QQLNWETAKL HCESQGANLA
SIHSEQEETI ITTGVTGADQ SYAFWIGLKR QDDGMMGWSD KTPLSFTDWG NDEPNNHNGR
EECTEAYLSP DSQYWNDLNC DAARNWICKV ERAYTPPTGT LSPQICGSDV DWVAYTSSYT
QQQKCYYFAN NPVKSWKSAN DYCATLGGSL VTIQTLDEQE FVTARVGGGG CINALWIGMV
QDGMNGPYVW IDGTPLTFEN WIGGQPNDNN GKELCVLMYT YAGLWSDDNC GLPNGFICQK
RTTATPGMPA PTPVVPGGCP AGWTTYGSKC YLEVGLTDNS LRKNWNDAEA YCNNNHAYLA
SVPNAYYNSF LTSQLFGATI NIWIGFNAQG TSRTFKWSDN EDVTYTNWAP NEPNNSGGLY
SYLEECGEII WSSDKAGQWN DIPCTEVRPF FCNIFRSTEF SQDNNPAAPD CPPNHNFVQW
DTGCYKTYTD MNGYKSWNDA SMACANEGTQ MASVWNVYEE SFIHSMFWPQ EGTTNFDSMW
IGLNFQYNSS TGATSYQWSD GSPVVYTKWG TNEPQNPTNG QGCAHMDNKG LWYMNTNIGE
CSSMKLAYVC KHETCIYTVV IPPQTPGIGE CEATWLPLGD YCYSIEFVMQ RSFGDAGAEC
QSRMAYLASV HSDIENKALL SWLNEKTAWL GLKRNGWGGW DWVDGTAVDY TNWGESEPNN
AGETGEACVE MYNNGKWNDN FCSNLRGYVC KKHK
//
