ID H2XKH1_CIOIN Unreviewed; 302 AA.
AC H2XKH1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000030153.1, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000030153.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2XKH1; -.
DR STRING; 7719.ENSCINP00000030153; -.
DR Ensembl; ENSCINT00000032567.1; ENSCINP00000030153.1; ENSCING00000020464.1.
DR GeneTree; ENSGT00940000161899; -.
DR HOGENOM; CLU_010208_2_0_1; -.
DR InParanoid; H2XKH1; -.
DR OMA; PERTHCI; -.
DR Proteomes; UP000008144; Unplaced.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR PANTHER; PTHR45920; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR PANTHER; PTHR45920:SF8; FORMIN-C; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT DOMAIN 1..302
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
SQ SEQUENCE 302 AA; 34544 MW; C2952BE609291328 CRC64;
MKPLYWIRLN QSHSNQTIEQ KKTLWENVEV VKLDEVDLVN LFAKTSSTKQ KKPLNTTIGQ
KKKKKEKFGK VLDLKRSQAV GIFISSLHID VDDIQNAILT LDTSIVDVEI MEAIWEIRPQ
LGEMEKIEHF VGTQKKVDED QRLSLDRPEE FLYKLWQIPD LSHRLFCITF MSRFDQDVSH
VTQTIALIND VCKTLRGDVV KKLLSIILSV GNYLNGGNVS RGQARGFDLE ILGKLKDVKS
NVGGVTLLSY IVSLYIRHFK QDNDLETWKA PVPDTLSLMR ASQVKYEDIC GEITKLKTKL
NG
//
