ID H2XV81_CIOIN Unreviewed; 354 AA.
AC H2XV81;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Programmed cell death protein 2-like {ECO:0000313|Ensembl:ENSCINP00000033565.1};
GN Name=LOC100186258 {ECO:0000313|Ensembl:ENSCINP00000033565.1};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000033565.1, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000033565.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2XV81; -.
DR STRING; 7719.ENSCINP00000033565; -.
DR Ensembl; ENSCINT00000030542.1; ENSCINP00000033565.1; ENSCING00000021521.1.
DR GeneTree; ENSGT00940000158339; -.
DR HOGENOM; CLU_034893_1_0_1; -.
DR InParanoid; H2XV81; -.
DR OMA; MPGPWAD; -.
DR TreeFam; TF354282; -.
DR Proteomes; UP000008144; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IBA:GO_Central.
DR InterPro; IPR007320; PDCD2_C.
DR PANTHER; PTHR46421; PROGRAMMED CELL DEATH PROTEIN 2-LIKE; 1.
DR PANTHER; PTHR46421:SF1; PROGRAMMED CELL DEATH PROTEIN 2-LIKE; 1.
DR Pfam; PF04194; PDCD2_C; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT DOMAIN 232..318
FT /note="Programmed cell death protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04194"
SQ SEQUENCE 354 AA; 40032 MW; 60790CDECC13117F CRC64;
YVIMTEFVLI GVPDSEMKQN HASWSTNKIG GFPDWMSIVT SQPSCSRCSK AQRFMLQIYC
PLENSKYHRT LYVFCCTQKQ CWSDSSGSNW KVYRDQMMEK VEAGPPIVKG STEGESWGLG
DDDWGDEGFP SPTNGDFPVA EQTCEPEQQM KDEKLHSFIH SIQPSWLMYN PRYIDVFNES
DLISPLEGDK HIADLISKYE TSASQSKDED LFAGCSAATE TYEKNEQKVK NRAFHKFHKK
ISLLPHQCIR YNYGGSPLLL SDCDVTMSIP PCSSCGKSLT FEFQLLPGLL PTVHIDGEEN
PVEFGTILVY TCSHNCWGNR DSPQIGGHVV YCPDPDLKFF KSQKFNEKIK NSGV
//
