ID H2XVD0_CIOIN Unreviewed; 535 AA.
AC H2XVD0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000033614.1, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000033614.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; EAAA01000271; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2XVD0; -.
DR STRING; 7719.ENSCINP00000033614; -.
DR Ensembl; ENSCINT00000033316.1; ENSCINP00000033614.1; ENSCING00000021005.1.
DR GeneTree; ENSGT01050000244924; -.
DR HOGENOM; CLU_015171_7_1_1; -.
DR InParanoid; H2XVD0; -.
DR OMA; AANNNAC; -.
DR TreeFam; TF319824; -.
DR Proteomes; UP000008144; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0043484; P:regulation of RNA splicing; IBA:GO_Central.
DR CDD; cd12693; RRM2_PTBP1_like; 1.
DR CDD; cd12423; RRM3_PTBP1_like; 1.
DR CDD; cd12425; RRM4_PTBP1_like; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592:SF27; HEPHAESTUS, ISOFORM Y; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13893; RRM_5; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 4.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 51..125
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 342..416
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 459..533
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 535 AA; 58971 MW; 3739B7BA481BAB26 CRC64;
SYVEMIVMEM LSSSSGSKRI NEDLACFTSG SINNGAKKIR TDRINSDQVS KVIHIRSLPS
DVSEQEVIQL GLSFGKVTNL LMLKGKNQAF LEMENSEVAR EMVNECAISP PTIRQRVLYV
QYSNHKELKT DSSPNQVKAQ AVLQAMQQTE GGPNHVLRVV VENMLYPITL DVLHTIFTKF
GVVLKTITFT KNNQFQALLQ MGDAIQSQTA KLSLDGQNIY NGCCTLRIEY SKLPALNVKY
NNDKSRDYTR NDLPSGESSI LNNPPSSLQS ILSSSAGLMP TPYSNNAAAS IAAALQQSQL
NTLSNAVSSR SAINNAAVAA QLANLINSGG STSSSMPSSG TSVLHVSNLN EDMISPQILF
TLFGVYGDVI RVKIMFQRKS NALIQMNDNT QAHVAMKHLH GVKLFGNSLQ VVTSKHSQVQ
MPREGQDIGN LTQDFSNSPL HRFKKPGSKN FQNIYPPSEV LHLSNIPNDV TEEFLKDSFA
AFGKVHGFKF FAKDRKMALI QMSTVEEAVK SLVMMHNFRL SDTNHLRVSF SKSQI
//
