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Database: UniProt
Entry: H2XZM0_CIOIN
LinkDB: H2XZM0_CIOIN
Original site: H2XZM0_CIOIN 
ID   H2XZM0_CIOIN            Unreviewed;      1729 AA.
AC   H2XZM0;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-OCT-2019, entry version 44.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCINP00000035104};
GN   Name=LOC100179612 {ECO:0000313|Ensembl:ENSCINP00000035104};
OS   Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000035104, ECO:0000313|Proteomes:UP000008144};
RN   [1] {ECO:0000313|Proteomes:UP000008144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12481130; DOI=10.1126/science.1080049;
RA   Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B.,
RA   De Tomaso A., Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M.,
RA   Harafuji N., Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T.,
RA   Lemaire P., Martinez D., Meinertzhagen I.A., Necula S., Nonaka M.,
RA   Putnam N., Rash S., Saiga H., Satake M., Terry A., Yamada L.,
RA   Wang H.G., Awazu S., Azumi K., Boore J., Branno M., Chin-Bow S.,
RA   DeSantis R., Doyle S., Francino P., Keys D.N., Haga S., Hayashi H.,
RA   Hino K., Imai K.S., Inaba K., Kano S., Kobayashi K., Kobayashi M.,
RA   Lee B.I., Makabe K.W., Manohar C., Matassi G., Medina M.,
RA   Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA   Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA   Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A.,
RA   Stainier D., Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K.,
RA   Yoshizaki F., Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C.,
RA   Doggett N., Glavina T., Hawkins T., Richardson P., Lucas S.,
RA   Kohara Y., Levine M., Satoh N., Rokhsar D.S.;
RT   "The draft genome of Ciona intestinalis: insights into chordate and
RT   vertebrate origins.";
RL   Science 298:2157-2167(2002).
RN   [2] {ECO:0000313|Ensembl:ENSCINP00000035104}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15114417; DOI=10.1007/s00239-003-2559-6;
RA   Gissi C., Iannelli F., Pesole G.;
RT   "Complete mtDNA of Ciona intestinalis reveals extensive gene
RT   rearrangement and the presence of an atp8 and an extra trnM gene in
RT   ascidians.";
RL   J. Mol. Evol. 58:376-389(2004).
RN   [3] {ECO:0000313|Ensembl:ENSCINP00000035104}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; EAAA01002091; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSCINT00000031842; ENSCINP00000035104; ENSCING00000022449.
DR   eggNOG; KOG0548; Eukaryota.
DR   eggNOG; ENOG410XTCJ; LUCA.
DR   GeneTree; ENSGT00940000156428; -.
DR   InParanoid; H2XZM0; -.
DR   OMA; LEISHET; -.
DR   TreeFam; TF328344; -.
DR   Proteomes; UP000008144; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.10; -; 5.
DR   InterPro; IPR024983; CHAT_dom.
DR   InterPro; IPR013026; TPR-contain_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR041617; TPR_MalT.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF12770; CHAT; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   Pfam; PF17874; TPR_MalT; 1.
DR   SMART; SM00028; TPR; 19.
DR   SUPFAM; SSF48452; SSF48452; 7.
DR   PROSITE; PS50005; TPR; 17.
DR   PROSITE; PS50293; TPR_REGION; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008144};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN       12    113       TPR_REGION. {ECO:0000259|PROSITE:
FT                                PS50293}.
FT   REPEAT       12     45       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT       46     79       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT       80    113       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   DOMAIN      188    261       TPR_REGION. {ECO:0000259|PROSITE:
FT                                PS50293}.
FT   REPEAT      188    221       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      228    261       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   DOMAIN      346   1022       TPR_REGION. {ECO:0000259|PROSITE:
FT                                PS50293}.
FT   REPEAT      346    379       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      426    459       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      506    539       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      546    579       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      586    619       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      626    659       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      666    699       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      786    819       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      829    862       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      909    942       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      949    982       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   REPEAT      989   1022       TPR. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00339}.
FT   COILED      352    372       {ECO:0000256|SAM:Coils}.
FT   COILED      679    699       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1729 AA;  192839 MW;  B4520E3DBDC9A06E CRC64;
     MESPHKETCP SPQDIAKSAK TACSNKQFEL ADQLYTEAIS HQPNNAILYC NRSVVKIHLK
     KYEDALQDAN TSIRLNRMHA KGYFHGGVAL KHLGHTYSAL VMYSNGMVLD SKNRKFLKEI
     IETSMLPPLN SYLSPVMTQL KEMNLNHNPF VIISVVGQAL LAQKETQRAV EVLECAVAVG
     TCSLKLKGSV YSTLSNALWT LGHFSRAIHY MTEDLKVAEL LMDAHGECRS LENLGFAFYT
     QRRYQEAFEV YTKQLGIAKI LKNKIQILSA CNGLERIYAG LSSQGPNSPK SSHTNVSLPL
     RKSDNGFLFN EVPEENNEQD TLSLAQYQEK LEILLKSPGA DKYEEAQLYC DIARAYKNVK
     RYDKQIESLK KSAIISRELF DVNSESRTLM CLAHAAKCAD DTSVSKEAYE RMLEISHETK
     DILLQGFASS HLGVLHHQLE NYEVAIKYHH KYLQIATNVQ DISSQGHAHG NLGNSYNALG
     FYEKAAHHQL KHVEISHKIL DEQVECSAHG NLAVAYQALK QTDKALEHFR LQLELSRRIK
     SCVNESVALM NLANCFCTTA MFSEAVEMYK GYLQLSVRVP DKHGEGRALY NLGYAYFSLG
     DHASAVDCYN ECISVASQCN DDVTMARAFC NLGLAKKDLG DLDAALEFQK KFLETSLEIR
     SARGVFKALG NIGDLYFERK ELDDAVKFYQ QQLETAQENK NPVLTAQACA SLAIALRLMG
     EKEKAVEIHK KEIGLYSSVI KDSKNEEEAR KRLNVTLAET LQICDEAKSG VNKEVAKSEA
     EWVAEAQAWR NLGITYTNMN KMEQALECFT NQMLSLRMVS SVTVSVEKVN SFCYLGDTCH
     AMEKYKEAIG HFKYALTLAE SLKHPKLENQ ACKGLFKAYK KNGEFEFAIQ YCEQSLVYCQ
     KLRDQKWLAS VYGELGNLYS EVCEYDKAVE ALMLQVKVGT ELESNEILAD SASDLGFIYY
     STANYEKALE FHYLDLEISK KSKNQTCQGR AHKNLALTYE ANKNYAASMF HYEQHLFIAE
     EQSDTLAKVE ALHGIGRCLL MQGNGDLSRA ILLLQQSMLI GRELNIECLI ASIACDLGKA
     LWVSNGSETA TSYLNQAFIA GKTDCFNMLA NEEKNSVVFR GKILKTYEKL LQYASVLLCN
     LVENNLNSEA FQLACEVSAL PEKVFSHKNT SPHTISNSLL LKSTQSNDGG NNLTAFFTVT
     AGTLFYWLLK DGNLCLSGHK PLYTEDDDNI LANLIFKLRE NVGVEITSDG KSLEGNMSKE
     SSLYTELLQL HSKFNNQSGF LKTGKGLIFN STVRDIKKYN SAKNPAFLLY ELLFSDMEKE
     MTSAVEKSPL ATFTLHIDGD LLLLPFPLLK KNNGDKFLYE KFQLTVLPIS STKTPSSSVF
     QCCPARALVS GNSGLKISRH DFSPAAAEAE TSLVSEILRV EPLLGNNATL QNVLEKLNRE
     QYECIHLACP FFTLPCGVVM EKSKVLEKDQ TTEDDQFVLT DRNILNANLT QTKLVVLASP
     YGLTISANIS NWSAAVFTIL RTFLTAGTKA ILLPLWPVPE TACKLFYKTF YGYLINGCDS
     GKALVHSMSS LRNSAQFQHP SFWAGFALFG QPAKIYPQDL PTTFALTKLL QGNPLHLKDT
     IKLCSHMLGK ALSEKVASGS SSPVPIYTTQ ESVAAKVHNT GGWRELFSAA GFQLRNKLED
     LPAAVVFPQS QPHVQRVLKT LKPFANLPCA ILETLGQLML SPYTSQAIL
//
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