GenomeNet

Database: UniProt
Entry: H2Y0I7_CIOIN
LinkDB: H2Y0I7_CIOIN
Original site: H2Y0I7_CIOIN 
ID   H2Y0I7_CIOIN            Unreviewed;       620 AA.
AC   H2Y0I7;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   28-MAR-2018, entry version 35.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCINP00000035421};
OS   Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000035421, ECO:0000313|Proteomes:UP000008144};
RN   [1] {ECO:0000313|Proteomes:UP000008144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12481130; DOI=10.1126/science.1080049;
RA   Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B.,
RA   De Tomaso A., Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M.,
RA   Harafuji N., Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T.,
RA   Lemaire P., Martinez D., Meinertzhagen I.A., Necula S., Nonaka M.,
RA   Putnam N., Rash S., Saiga H., Satake M., Terry A., Yamada L.,
RA   Wang H.G., Awazu S., Azumi K., Boore J., Branno M., Chin-Bow S.,
RA   DeSantis R., Doyle S., Francino P., Keys D.N., Haga S., Hayashi H.,
RA   Hino K., Imai K.S., Inaba K., Kano S., Kobayashi K., Kobayashi M.,
RA   Lee B.I., Makabe K.W., Manohar C., Matassi G., Medina M.,
RA   Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA   Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA   Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A.,
RA   Stainier D., Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K.,
RA   Yoshizaki F., Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C.,
RA   Doggett N., Glavina T., Hawkins T., Richardson P., Lucas S.,
RA   Kohara Y., Levine M., Satoh N., Rokhsar D.S.;
RT   "The draft genome of Ciona intestinalis: insights into chordate and
RT   vertebrate origins.";
RL   Science 298:2157-2167(2002).
RN   [2] {ECO:0000313|Ensembl:ENSCINP00000035421}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15114417; DOI=10.1007/s00239-003-2559-6;
RA   Gissi C., Iannelli F., Pesole G.;
RT   "Complete mtDNA of Ciona intestinalis reveals extensive gene
RT   rearrangement and the presence of an atp8 and an extra trnM gene in
RT   ascidians.";
RL   J. Mol. Evol. 58:376-389(2004).
RN   [3] {ECO:0000313|Ensembl:ENSCINP00000035421}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS01006510}.
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DR   EMBL; EAAA01002637; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSCINT00000032919; ENSCINP00000035421; ENSCING00000002065.
DR   GeneTree; ENSGT00760000119180; -.
DR   Proteomes; UP000008144; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; SSF48403; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00933366};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008144};
KW   Ion channel {ECO:0000256|SAAS:SAAS00790162};
KW   Ion transport {ECO:0000256|SAAS:SAAS00790154};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00788392}.
FT   TRANSMEM    254    275       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    287    310       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    325    342       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    363    382       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    413    437       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    458    478       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    550    570       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      297    583       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   620 AA;  71606 MW;  68ED9692747159A5 CRC64;
     NKNCRDQWGR SALFIAMLHL NTEMMELLLE YKQVEIDECL YHAIDFGYYD VVELFMKYDK
     KRNQVITGDD SFYPPGLTPI QLAAHKNDYV MLKILHSNGF NLEKPMLKTV LERAWDATNN
     DILYYRARAS PAYMDAHEHW DMLENLFSLY KKLKKKATDE PSAATLYRQL ASQVEDFACD
     LLSEVRSPTD LTDLLRFDPP GHDQLSIHRH YLNPVERACE VRMKSFVAHE NCQLALSTLR
     QGTLFECDNG WRPFIVRTIL AFLFPIISLA FIIAPNSKPG RLLRNPMVNL SCHIASEISF
     LLLMIIRLIL LTNAKCDCLG QKPGAVDYIV FVWVIAKGYR YFNRLRVSPT IQFMTNVWNM
     NDSGMIFLSL VIAVMTIVDT QVTKGLMRSR NLNPDGFDLC NRETWELEFA WPVYISEVCY
     ALIYILIFVR AMELLYIDRT LGPLQLSLDK MMVDIFRFLV LFAVTFMAFA FGMTQLYWAY
     GTYSDLCYCN KEVCGDTFDS SSFTCYPVYS SIIDSILEQY WTLYGYGYGA EPTAAVKVPG
     QSTITLPSGL ILSMVFHMWA VVVMLNMLIA MMSHSFDRVR DNAEIEWKYH RSGMWMRYVK
     VNVCPRPCPM NLLPTVQSIV
//
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