ID H2Y9X9_CIOSA Unreviewed; 1179 AA.
AC H2Y9X9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=SAM domain-containing protein {ECO:0000259|PROSITE:PS50105};
OS Ciona savignyi (Pacific transparent sea squirt).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000002127.1, ECO:0000313|Proteomes:UP000007875};
RN [1] {ECO:0000313|Proteomes:UP000007875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E., Ait-zahra M.,
RA Allen N., Allen T., An P., Anderson M., Anderson S., Arachchi H.,
RA Armbruster J., Bachantsang P., Baldwin J., Barry A., Bayul T.,
RA Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L., Borowsky M.,
RA Boukhgalter B., Brunache A., Butler J., Calixte N., Calvo S., Camarata J.,
RA Campo K., Chang J., Cheshatsang Y., Citroen M., Collymore A., Considine T.,
RA Cook A., Cooke P., Corum B., Cuomo C., David R., Dawoe T., Degray S.,
RA Dodge S., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N., Dupes A.,
RA Elkins T., Engels R., Erickson J., Farina A., Faro S., Ferreira P.,
RA Fischer H., Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G.,
RA Gnerre S., Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K.,
RA Hafez N., Hagopian D., Hagos B., Hall J., Hatcher B., Heller A.,
RA Higgins H., Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E.,
RA Iliev I., Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M.,
RA Karlsson E., Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E.,
RA Labutti K., Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O., Lui A.,
RA Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J., Manning J.,
RA Marabella R., Maru K., Matthews C., Mauceli E., Mccarthy M., Mcdonough S.,
RA Mcghee T., Meldrim J., Meneus L., Mesirov J., Mihalev A., Mihova T.,
RA Mikkelsen T., Mlenga V., Moru K., Mozes J., Mulrain L., Munson G.,
RA Naylor J., Newes C., Nguyen C., Nguyen N., Nguyen T., Nicol R., Nielsen C.,
RA Nizzari M., Norbu C., Norbu N., O'donnell P., Okoawo O., O'leary S.,
RA Omotosho B., O'neill K., Osman S., Parker S., Perrin D., Phunkhang P.,
RA Piqani B., Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V.,
RA Raymond C., Retta R., Richardson S., Rise C., Rodriguez J., Rogers J.,
RA Rogov P., Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA Spencer B., Stalker J., Stange-thomann N., Stavropoulos S., Stetson K.,
RA Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P., Tenzing P.,
RA Tesfaye S., Theodore J., Thoulutsang Y., Topham K., Towey S., Tsamla T.,
RA Tsomo N., Vallee D., Vassiliev H., Venkataraman V., Vinson J., Vo A.,
RA Wade C., Wang S., Wangchuk T., Wangdi T., Whittaker C., Wilkinson J.,
RA Wu Y., Wyman D., Yadav S., Yang S., Yang X., Yeager S., Yee E., Young G.,
RA Zainoun J., Zembeck L., Zimmer A., Zody M., Lander E.;
RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAVP00000002127.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
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DR AlphaFoldDB; H2Y9X9; -.
DR Ensembl; ENSCSAVT00000002164.1; ENSCSAVP00000002127.1; ENSCSAVG00000001250.1.
DR GeneTree; ENSGT01050000244900; -.
DR Proteomes; UP000007875; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF20; LIPRIN-ALPHA, ISOFORM E; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007875}.
FT DOMAIN 875..941
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1004..1061
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1085..1154
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1157..1179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 28..126
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 241..433
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 487..514
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 756..771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1179 AA; 135061 MW; 3ACFACA135B52E38 CRC64;
MMCDIMPTIS EDRTSNIGAD GAEEEEDKAN LEQLMVTVLD ERDKLVENLQ EVKENLANTN
AKLDEVEKER QFLLKQLNTS MPPDYASLTK ELNHARERIL ECTEEIDDMK SERNNTRLLL
EHLETLVARH ERSLRMTVVK RQQQQNAGVS SEVEVLKALK SLFEHHKALD EKVREKLKAA
LEREMHLEEL LESSSRETKV LREQVNQLKL QNQNGSDESL KKSNNIKVKD RNPMTNGNCE
LEEEANRIVL LQETNDKQAA ELIHVRQRVN TMLSRTAELE ESLQVARKDL MKSEELNNRT
QKEYRDVNKS RLEIDERVTT LERRYLNAQR EAASVHELND RLEAELANRD AAVRQLEERN
DILQDRIKSA DQKLQQSLRR AEALPEVVEA ELAQRVAALT KAEERHGNVE ERLKSMESKL
EEKTQELLRA RQREKMNEEH NQRLSSTVDR LLAESNERLQ LHLKEKMASL EEKNSLSSDF
EKVKKLLEDS VLDKERLQRS MDKLHSELNI YKASKTSSLD RSSMSNITHT MPSRTVQSMP
RVTGSTPDLT HHQSYLRTAK ARVDTLRTDP DKVHMLNEQE WERAQQADIL SQVQKAFEGI
INHCVFYVEI DDSIYSAVDL LSPVGQTDAH SLAHMLQDQL DAINQEIRYI LQEEKVSTER
RAEEIEHRVS EPRRPMFQLD SGAVVYPGGN LTPRSQPFCS HSSPCLHSRC RVTSLGHFGD
RGFTGSFSRL DWQLCIYTSN ACSVYLFHCS NSPPFPAPNS QNSSPARFDR SGQSRTLEPD
DSKMWKGTSS PVSNITSKKK SVIKSSIGRL FGKKDKVVEQ MSGSGSTVSV ADDRSTSNDS
LDVGSGHQRE QERRMKKKHE MLEEVRRCGT PFAAWNGPTV VAWLELWVGM PAWYVAACRA
NVKSGAIMSA LSDTEIQREI GISNPLHRLK LRLAIHEMIS LTSPSAPPTS RTTTGSVWMT
HEEVDSLANQ VPLTVFMNTI NVCPTYLHQT LAYGDMNHEW IGNEWLPSLG LAQYRSHFME
CLVDARMLDH LTKKDLRQHL KMVDGFHRSS LQFGILCLKR LNYNKKDLEQ RREQSADEIR
DVQVWSNQRV IRWLQGVGLR DYATRLSDSG IHGAVVALDN TFDAEAFALV LQIPNQNTQA
RQILEREFSN LVALGTERQL EPDEPDSKNF RRNPSWRKK
//
