ID H2YDF2_CIOSA Unreviewed; 836 AA.
AC H2YDF2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
OS Ciona savignyi (Pacific transparent sea squirt).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000003350.1, ECO:0000313|Proteomes:UP000007875};
RN [1] {ECO:0000313|Proteomes:UP000007875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E., Ait-zahra M.,
RA Allen N., Allen T., An P., Anderson M., Anderson S., Arachchi H.,
RA Armbruster J., Bachantsang P., Baldwin J., Barry A., Bayul T.,
RA Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L., Borowsky M.,
RA Boukhgalter B., Brunache A., Butler J., Calixte N., Calvo S., Camarata J.,
RA Campo K., Chang J., Cheshatsang Y., Citroen M., Collymore A., Considine T.,
RA Cook A., Cooke P., Corum B., Cuomo C., David R., Dawoe T., Degray S.,
RA Dodge S., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N., Dupes A.,
RA Elkins T., Engels R., Erickson J., Farina A., Faro S., Ferreira P.,
RA Fischer H., Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G.,
RA Gnerre S., Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K.,
RA Hafez N., Hagopian D., Hagos B., Hall J., Hatcher B., Heller A.,
RA Higgins H., Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E.,
RA Iliev I., Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M.,
RA Karlsson E., Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E.,
RA Labutti K., Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O., Lui A.,
RA Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J., Manning J.,
RA Marabella R., Maru K., Matthews C., Mauceli E., Mccarthy M., Mcdonough S.,
RA Mcghee T., Meldrim J., Meneus L., Mesirov J., Mihalev A., Mihova T.,
RA Mikkelsen T., Mlenga V., Moru K., Mozes J., Mulrain L., Munson G.,
RA Naylor J., Newes C., Nguyen C., Nguyen N., Nguyen T., Nicol R., Nielsen C.,
RA Nizzari M., Norbu C., Norbu N., O'donnell P., Okoawo O., O'leary S.,
RA Omotosho B., O'neill K., Osman S., Parker S., Perrin D., Phunkhang P.,
RA Piqani B., Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V.,
RA Raymond C., Retta R., Richardson S., Rise C., Rodriguez J., Rogers J.,
RA Rogov P., Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA Spencer B., Stalker J., Stange-thomann N., Stavropoulos S., Stetson K.,
RA Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P., Tenzing P.,
RA Tesfaye S., Theodore J., Thoulutsang Y., Topham K., Towey S., Tsamla T.,
RA Tsomo N., Vallee D., Vassiliev H., Venkataraman V., Vinson J., Vo A.,
RA Wade C., Wang S., Wangchuk T., Wangdi T., Whittaker C., Wilkinson J.,
RA Wu Y., Wyman D., Yadav S., Yang S., Yang X., Yeager S., Yee E., Young G.,
RA Zainoun J., Zembeck L., Zimmer A., Zody M., Lander E.;
RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAVP00000003350.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2YDF2; -.
DR Ensembl; ENSCSAVT00000003401.1; ENSCSAVP00000003350.1; ENSCSAVG00000001995.1.
DR GeneTree; ENSGT00940000171565; -.
DR HOGENOM; CLU_014106_0_0_1; -.
DR OMA; EXKEYKK; -.
DR Proteomes; UP000007875; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR CDD; cd11789; SH3_Nebulin_family_C; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR013998; Nebulin-like.
DR InterPro; IPR000900; Nebulin_repeat.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR11039:SF64; LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11039; NEBULIN; 1.
DR Pfam; PF00880; Nebulin; 11.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00510; NEBULIN.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00227; NEBU; 16.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51216; NEBULIN; 13.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007875};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 777..836
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 64..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 836 AA; 95510 MW; 57D5F8F4C8B2397E CRC64;
YREEYNKEKG QGMVYNPEIP TYQLARKVRT LASDNLYKDK AAQLLHQYSV IPDTPQLTFA
KTVAQQSSDN KYKEEYEKEK GHGASNLHET PQMKHALEVA KLTSDNVYTK KAEQGRHTFK
LTTDQPNFKQ AKVANDLISD LKYRQPHKGK GAKVKDARDV PSILHSKKMQ EMFSGKRYRN
EYEKIKDQYN LDVASPSFVN AKRASQLLSD VTYKEEYNKE KGQPFASYQD SFQMKHLRTL
PEKLSDSGYK QKAKAEQQHY LMIPDDPEFI RLKEAAQYLS DIAYKGEAQK ENTRYTSVPD
TPVMLKAKES QALQSDLEYR KEFDKEIKGK GWKIKDTPQQ KHAQEIGKVQ SQIDYRKQAR
EINARGTNIS GDVTPSSLHH KRAQEILDDR KYKADYERTV KGRGMTFDLH GTPSMNHIKR
AEDIKSDILY KESYEASKGR PTVVLDAPHI IHAQKANDLI SDVKYKQNYN ESRGHVHSMM
ETPETKRVKE NQQYLSQVNY KSDVESMKGQ HHSSVMDTPE LRQIKMNSYN FSDVHYKSGA
ESMKTVNQSC VMDTPELRRV RQNTYNFSAV SFSSSFTLLA TKGKSVGVCL DTPELRTARQ
NSKNFSQIKY QSDFANMKGK YTPVADDINM QRVKHATRIS SDLSYKGMKA KNVEMDKMLK
NRDTGAAKSK PMKRWNRNPG SIFDYDPSDY ETDAEYEMGR YRNNSGTNSF SCLSLSFSYY
LLSHQLLLNI WKTAPSGGGS VGTKFHLFPL PCYMTGYDAH VACLTGVGGS FRSRDSIGVK
QFQAMYDYSA ADDDEVTFRD GDVIVNAQSI DDGWMFGTVL RTGATGMLPA NYVQMM
//
