GenomeNet

Database: UniProt
Entry: H2YYU4_CIOSA
LinkDB: H2YYU4_CIOSA
Original site: H2YYU4_CIOSA 
ID   H2YYU4_CIOSA            Unreviewed;      2776 AA.
AC   H2YYU4;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   16-JAN-2019, entry version 38.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000010505};
OS   Ciona savignyi (Pacific transparent sea squirt).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000010505, ECO:0000313|Proteomes:UP000007875};
RN   [1] {ECO:0000313|Ensembl:ENSCSAVP00000010505}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E.,
RA   Ait-zahra M., Allen N., Allen T., An P., Anderson M., Anderson S.,
RA   Arachchi H., Armbruster J., Bachantsang P., Baldwin J., Barry A.,
RA   Bayul T., Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L.,
RA   Borowsky M., Boukhgalter B., Brunache A., Butler J., Calixte N.,
RA   Calvo S., Camarata J., Campo K., Chang J., Cheshatsang Y., Citroen M.,
RA   Collymore A., Considine T., Cook A., Cooke P., Corum B., Cuomo C.,
RA   David R., Dawoe T., Degray S., Dodge S., Dooley K., Dorje P.,
RA   Dorjee K., Dorris L., Duffey N., Dupes A., Elkins T., Engels R.,
RA   Erickson J., Farina A., Faro S., Ferreira P., Fischer H.,
RA   Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G., Gnerre S.,
RA   Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K., Hafez N.,
RA   Hagopian D., Hagos B., Hall J., Hatcher B., Heller A., Higgins H.,
RA   Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E., Iliev I.,
RA   Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M., Karlsson E.,
RA   Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E., Labutti K.,
RA   Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA   Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O.,
RA   Lui A., Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J.,
RA   Manning J., Marabella R., Maru K., Matthews C., Mauceli E.,
RA   Mccarthy M., Mcdonough S., Mcghee T., Meldrim J., Meneus L.,
RA   Mesirov J., Mihalev A., Mihova T., Mikkelsen T., Mlenga V., Moru K.,
RA   Mozes J., Mulrain L., Munson G., Naylor J., Newes C., Nguyen C.,
RA   Nguyen N., Nguyen T., Nicol R., Nielsen C., Nizzari M., Norbu C.,
RA   Norbu N., O'donnell P., Okoawo O., O'leary S., Omotosho B.,
RA   O'neill K., Osman S., Parker S., Perrin D., Phunkhang P., Piqani B.,
RA   Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V., Raymond C.,
RA   Retta R., Richardson S., Rise C., Rodriguez J., Rogers J., Rogov P.,
RA   Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA   Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA   Spencer B., Stalker J., Stange-thomann N., Stavropoulos S.,
RA   Stetson K., Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P.,
RA   Tenzing P., Tesfaye S., Theodore J., Thoulutsang Y., Topham K.,
RA   Towey S., Tsamla T., Tsomo N., Vallee D., Vassiliev H.,
RA   Venkataraman V., Vinson J., Vo A., Wade C., Wang S., Wangchuk T.,
RA   Wangdi T., Whittaker C., Wilkinson J., Wu Y., Wyman D., Yadav S.,
RA   Yang S., Yang X., Yeager S., Yee E., Young G., Zainoun J., Zembeck L.,
RA   Zimmer A., Zody M., Lander E.;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCSAVP00000010505}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   STRING; 51511.ENSCSAVP00000010505; -.
DR   Ensembl; ENSCSAVT00000010632; ENSCSAVP00000010505; ENSCSAVG00000006185.
DR   eggNOG; KOG3533; Eukaryota.
DR   eggNOG; ENOG410XR97; LUCA.
DR   GeneTree; ENSGT00940000167397; -.
DR   InParanoid; H2YYU4; -.
DR   OMA; PRHAPYK; -.
DR   TreeFam; TF312815; -.
DR   Proteomes; UP000007875; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007875};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007875};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2311   2333       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2354   2381       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2387   2407       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2419   2439       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2476   2496       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2602   2625       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      119    173       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      180    230       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      238    294       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      398    454       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED       96    116       {ECO:0000256|SAM:Coils}.
FT   COILED     2733   2767       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2776 AA;  315484 MW;  561181E011F2FB58 CRC64;
     FCRQAVMASS FLHIGDVISL FAEGSGPNSV CGFISTLGLV DDRCVVQPDA GNLQNPPKKF
     RDCLFKICPM NRYNAQKQFW KTLKSGATRI ADAVIMKRLQ ESAGVEKDQN ERENQKLLGQ
     VVKYGSVVQL LHLKSNKYLT VNKRLPALLE KNAMRVSLDP DGNEGSWFYI QLFYKLRSTG
     DNVVIGDKVV IMPVNAGQPL HASKCELADN PGCKEVNSVS CNTSWKIVLF MTWEDDRKDV
     LKGGDVVRMF HAEQEKFLTC DEYRRSLHVF LRTTGRMSAT SATSSKALWE IEVVQKDPCQ
     GGAGHWNNLF RFKHLASGNY LAAKVTIFIF IGMAVERSST GVELLCEIEN GGSSEKESSR
     SRNRAPPVGM SFCLVATAES SSVSSIFELD PTSFTKSDAL VPSNSYVRLK HLCTDTWVHS
     TMIPIDKEED RPVMLKVSGG GYKEDKEAFA IVNVNVEEVR DLDFANDSSK VLADCAKDME
     TKQITVNERR FVIKLLEDLI FFVARQPRGA MDALDVMVVD PDRERQKLLR EQNILKQVFK
     ILQAPFKDSG DGALLHLDEL RDKKNVHYQH MLKLCYRLLR HSTQDYRKNQ EYIAKSFGLM
     QQQIGHDILA EDTITALLHN NRKLLEQHIT GTEIETFVAL VRKNREPRFL DYLADLCVTN
     KQAIPKTQEL ICRNILALKN KDILIETNAA IILQCFITMS ALDIWLTCLF INNSRNPQRN
     KLQHQTVSVS ITQNLINSPE ILGIDESGEE VALLSYGDGK AVEKSIRHLA QSNILDDKTV
     LTYYRHQLDL FSKMCLDRQY LAINPISEEL TIPIILKCMA DTQLPYDLRA SFVQLMLHMH
     VDKEPQEQVI PVQYARLWSG IPNQININDY DNDVGRHGFE KFVPTMQFVE EYLNSFVNNA
     WIFKNKKENK LTFEVVNLAR HLIYFGFYSF ADLLSLNRTL LQILDCVNGV PTNLFNGRIA
     DTGSCLPTTV NRSGVDAVSR GVGNIGLLVS TMTLGGTLPP QSGGNETTPQ NPSSPSIHMN
     SHDEYVLETK LKIIEILHFI LDVRLDYRIS LLSIFKREFD ENNGRQRELP SSADSSTQSE
     GRVIKITIIN GFSFSNLAVG TCAPPPINLG VISAKSEGIF DGSLESSDLD LDEDGGRMFL
     RVLLNLVMHD YPPLVSGALQ LLFRHFSQRQ EVLGAFKNVQ LLVTKDEHEN YTEIKRNLDQ
     LRLLVEKSEL WVWKGKSQNT TSNPREIVDY APVLDANRPS IKSSSLKNYN TIKEILRKLA
     GLCTDASSEK PCKEQQRLLR NMGAHGVVLD LLQISYERGT DEEMQRVMTQ AHRFLQLFCK
     GNPQNQALLH KNLNLFMTPG LLEAETMQAI FQDNVALCKE VTHGVIQHFV HCIESHGRRT
     EYLRFLQAII KSEGKVHIRR CQDMVMAELV NTQAGEEVLL FYNDRASFTT FIKLMEDYAR
     DCALQSQLQQ TPDLDAEQSP LLYHIELCST ARFHTATEGK NVYTEIKCHS LLPLDDIVQV
     VTHESCIPEV KNAYVNFLNH CYVDTEVEMK EIYSSNHIWR LFDDFMEDME RVRSKEADDH
     IRKLQHYLAT TVMDIITMFF SSPFSDATTV IQTRQTTYNQ LLRSIAMLNQ SSHLLPQFKP
     KLEDTMKKMG EVAKDRKIAI PGALDTEVNG ALNRPTVLEV IKKFRSLRTS GSWREGEPTL
     GQSYRDIIEC LQDSVAVLDA QLRPLVQAEL SVLVDILHRP ELLFPVDTDA RKQCEGGGFI
     SKLIKHTEKL LEDREDKLCV KVLQTLREMM TVHISFNKGE ALRQILLSRY YGSNYHHLRD
     LAQRDNSSTR GSSTSIFRKT ELTLEEVQCH LKKEGATDLV INLIIGNYSE KIFHESVLLG
     IALLEGGNND NQTSFYNQLL QDQGSEKFFE VFHEKIEAAQ LELKNSSTVN ASECGSNFQQ
     PQTGSFIYNH LLNIIHTNFL LLAPELVEEL ADAAGQTKKA IENVQRPHVA SKSSSEPHST
     GESDRHDEEK TLSPVISIMK PILRFLQLLC ENHNAHLQNY LRTQNNKNSY NLVCDTLKFL
     DCICGSTTGG LGLLGLYINE HNVELINQTL ESLTEYCQGP CHDNQNAIAS HESNGIDIII
     ALILNDIIPL GKQRMDLVMQ LKNNASKLLL AIMESRHDSE NAERILRNIN HTQLVSVIEQ
     AYTKEEELEG VVGDSQLDMT GDGSPRAVGH NIYILAHQLA RHNTSLAQSL KPDNSLTGTE
     ALHYYKKHTA QIEIVRSDRT MEQIVFPVPH VCSYLTKETM DRVWNTTDRD EQGSKVGSFF
     KQTEDMYREM VWQKKLREYT SLYWFSRHIS LWSTISTNFI IIINILVALF YPFKTLDYKA
     WNDKAQLILW PSMLVSLAAI TNPLAVRCFT LCIMVKTIFW IGVQNALLIL GVLNLLNRFI
     YLLSFLGNKG MKDQGVMKVL METQFIIHVG HIFFCFIGLF WDELFYSILF FDLIYGEETL
     LNVIRSVTRN VRSLLLTAML ALILVYLFSI VGYLFLKQDF KVSVSPRCSS TSPERLQSLR
     DKLDKELRNT QVCRQDDGSC NSTGYLCDGG DSVEENHCES LLMCIITTLN EGLRNGGGIG
     DILRKPSQSE GILFMGRVVY DLLFFFILII IVLNLIFGVI IDTFADLRSE KQQKDDVLRN
     TCFICGLERK SFDNKTVSFE THVKEEHNMW HYLYFVVLVK VKDPTEFTGP ESYVYNQVKE
     RLLEWFPRMQ AMSLAADDDA VENNDVRGLL VQLEANSNLV KSLSAQLQDL QDQVTEQRRK
     QQRLNIINPH NNMQFN
//
DBGET integrated database retrieval system