ID H2Z6L8_CIOSA Unreviewed; 1941 AA.
AC H2Z6L8;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAVP00000013230.1};
OS Ciona savignyi (Pacific transparent sea squirt).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=51511 {ECO:0000313|Ensembl:ENSCSAVP00000013230.1, ECO:0000313|Proteomes:UP000007875};
RN [1] {ECO:0000313|Proteomes:UP000007875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E., Ait-zahra M.,
RA Allen N., Allen T., An P., Anderson M., Anderson S., Arachchi H.,
RA Armbruster J., Bachantsang P., Baldwin J., Barry A., Bayul T.,
RA Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L., Borowsky M.,
RA Boukhgalter B., Brunache A., Butler J., Calixte N., Calvo S., Camarata J.,
RA Campo K., Chang J., Cheshatsang Y., Citroen M., Collymore A., Considine T.,
RA Cook A., Cooke P., Corum B., Cuomo C., David R., Dawoe T., Degray S.,
RA Dodge S., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N., Dupes A.,
RA Elkins T., Engels R., Erickson J., Farina A., Faro S., Ferreira P.,
RA Fischer H., Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G.,
RA Gnerre S., Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K.,
RA Hafez N., Hagopian D., Hagos B., Hall J., Hatcher B., Heller A.,
RA Higgins H., Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E.,
RA Iliev I., Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M.,
RA Karlsson E., Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E.,
RA Labutti K., Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T.,
RA Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O., Lui A.,
RA Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J., Manning J.,
RA Marabella R., Maru K., Matthews C., Mauceli E., Mccarthy M., Mcdonough S.,
RA Mcghee T., Meldrim J., Meneus L., Mesirov J., Mihalev A., Mihova T.,
RA Mikkelsen T., Mlenga V., Moru K., Mozes J., Mulrain L., Munson G.,
RA Naylor J., Newes C., Nguyen C., Nguyen N., Nguyen T., Nicol R., Nielsen C.,
RA Nizzari M., Norbu C., Norbu N., O'donnell P., Okoawo O., O'leary S.,
RA Omotosho B., O'neill K., Osman S., Parker S., Perrin D., Phunkhang P.,
RA Piqani B., Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V.,
RA Raymond C., Retta R., Richardson S., Rise C., Rodriguez J., Rogers J.,
RA Rogov P., Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T.,
RA Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C.,
RA Spencer B., Stalker J., Stange-thomann N., Stavropoulos S., Stetson K.,
RA Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P., Tenzing P.,
RA Tesfaye S., Theodore J., Thoulutsang Y., Topham K., Towey S., Tsamla T.,
RA Tsomo N., Vallee D., Vassiliev H., Venkataraman V., Vinson J., Vo A.,
RA Wade C., Wang S., Wangchuk T., Wangdi T., Whittaker C., Wilkinson J.,
RA Wu Y., Wyman D., Yadav S., Yang S., Yang X., Yeager S., Yee E., Young G.,
RA Zainoun J., Zembeck L., Zimmer A., Zody M., Lander E.;
RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAVP00000013230.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 51511.ENSCSAVP00000013230; -.
DR Ensembl; ENSCSAVT00000013380.1; ENSCSAVP00000013230.1; ENSCSAVG00000007768.1.
DR eggNOG; KOG3544; Eukaryota.
DR GeneTree; ENSGT00940000165024; -.
DR HOGENOM; CLU_236608_0_0_1; -.
DR InParanoid; H2Z6L8; -.
DR OMA; SQCTFTC; -.
DR TreeFam; TF316872; -.
DR Proteomes; UP000007875; Unassembled WGS sequence.
DR CDD; cd00033; CCP; 26.
DR CDD; cd01450; vWFA_subfamily_ECM; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 28.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF567; LOCOMOTION-RELATED PROTEIN HIKARU GENKI; 1.
DR Pfam; PF00084; Sushi; 24.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00032; CCP; 27.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 27.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50923; SUSHI; 26.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000007875};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 1..57
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 58..123
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 131..190
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 191..256
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 257..320
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 321..383
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 384..446
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 447..509
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 581..643
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 644..709
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 710..775
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 776..838
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 839..904
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 905..970
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 971..1036
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1037..1099
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1100..1165
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1166..1228
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1229..1291
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1292..1357
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1358..1420
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1421..1486
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1531..1596
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1597..1662
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1663..1728
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1735..1797
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1806..1941
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DISULFID 28..55
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 161..188
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 1941 AA; 207999 MW; 153DD368C7B775C4 CRC64;
CDVLLIPLFG RMHCDITNKV GSVCLFSCEF GFHLVGNASI KCNSNLLWNA SVPMCYRTTC
KPIHADPVNG GVFCFNENNV GSQCVFSCED GYRVLGSATS TCNTNLHGGT DGVWTSPTPR
CIRKLTLFLA KRCYPVVRTV RYGRVSCTNW NKFGSVCSVT CNRGYFVEGR RQVTCSSNFF
WNNAPPRCIR ITCSPRYTDL YQGGIFCYNA NNLGSECIFE CELGFYMVGS PRVTCGLSTI
DDEIGEWSNP APTCEAIRCQ PPVTELLNGD VTCTDRNMVG SVCVFYCDPG FSITGEIATT
CEHVSSVTAE WTSRGQNCQR QECMPVGSIR NGEVGCTDGD STGSECSFTC NAVDGYKLTT
GNDSSNICLN NMNWDAERPC CAPITCQPRP LQPENGRVQC SDRNAVGSVC FYTCNAGYDR
VGEPAVTCND VSGSGQWSAS PPTCQLQQCQ PLSPPANGQI NCTNGNELGS LCQFTCDPNY
MLTGDPISEC VTGANGSPVF DNPPPICERK IIIVLNHGNI TTLQLNGTVV CTKPSLFVTV
CSFECISTFE LIGNVDLTCV GSQNGDGSGS WSSNPPICSP MECTLPPDPV NGSKVCNGGT
FLGAYCEFSC DPGFSLVGDT GSDCSETPDG NLAFNNPPPV CEPISCQPVY NTLDNGGVSC
TNSNMINSQC TFTCNPAYEL VGQTVLTCND VFNGDLNGQW SSEAPFCRTI SCQPVYNTLD
NGGVSCTNSN MINSQCTFTC NPAYELVGQT VLTCNDDFDG DLNGQWSSEA PFCRRMECTL
PPDPANGSKV CNGGTFLGAH CEFSCDPGFS LVGSSGSDCS ITPDGPLAFT NPPPVCEPIS
CQPVYNTLDN GGVSCTNSNM INSQCTFTCN PAYELVGQMV LTCNDDFDGD LNGQWSSEAP
FCRPISCQPV YNTLENGGAS CTNSNMINSQ CTFTCNPAYE LVGQMVLTCN DDFDGDLNGQ
WSSEAPFCRP ISCQPVYNTL DNGGVSCTNS NMINSQCTFT CNPAYELVGQ TVLTCNDDFD
GDLNGQWSSE APFCRRMECT LPPDPANGSK VCNGGTFLGA HCEFSCDPGF SLVGATGSDC
SITPDGNLAF TNPPPVCEPI SCQPVYNTLD NGGVSCTNSN MINSQCTFTC NPAYELVGQT
VLTCNDDFDG DLNGQWSSEA PFCRRMECTL PPDPANGSKV CNGGTFLGAH CEFSCNPGFS
LVGATGSDCS ETPDGNLAFT NPPPVCERME CTLPPDPVNG SKVCNGGTFL GAHCEFSCNP
GFSLVGATGS DCSETPDGNL AFTNPPPVCE PISCQPVYNT LENGGVSCTN SNMINSQCTF
TCNPAYELVG QMVLTCNDDF DGDLNGQWSS EAPFCRRMEC TLPPDPVNGS KVCNGGTFLG
AHCEFSCDPG FSLVGATGSD CSETPDGNLA FTNPPPVCEP ISCQPVYNTL ENGGVSCTNS
NMINSQCTFT CNPAYELVGQ TVLTCNDDFD GDLNGQWSSE APFCRSTFLG AHCEFSCDPG
FSLVGATGSD CSITPDGPLA FNNPPPVCEP ISCQPVYNEL NNGSVSCTNS NMINSQCTFT
CNPAYELVGQ MVLTCNDDFD GDLNGQWSSE APFCRPISCQ PVYNTLENGG VSCTNSNMIN
SQCTFTCNPA YELVGQMVLT CNDDFDGDLN GQWSSEAPFC RPISCQPVYN TMEHGGVSCT
NSNMINSQCT FTCNPGYELV GQMVLTCNDD FDGDLNGQWS SEAPYCQRED VLSDEPCPPI
GTIPNSELTC SDGTSQDSVC NLACDQTNGY FVYPPGSNQF TCQPSGVWNI PPPCCARDCL
GHAVVDLVFI LDSSTSIGSP NWETMKSFVK DIISSFDISA DQTRVSVFRY NRRVDRRSQI
LLNHYLNDKP GLLSAVEQIP YSGSGTYIGR ALQYARDHVL RYRNGDRHVK DVIVTLTDGR
SYDDVLPVSN QLRQFGATVN I
//
