ID H2ZSB9_LATCH Unreviewed; 308 AA.
AC H2ZSB9;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Interleukin 13 receptor subunit alpha 2 {ECO:0000313|Ensembl:ENSLACP00000000290.1};
GN Name=IL13RA2 {ECO:0000313|Ensembl:ENSLACP00000000290.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000000290.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000000290.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFYH01199128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01199129; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01199130; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2ZSB9; -.
DR STRING; 7897.ENSLACP00000000290; -.
DR Ensembl; ENSLACT00000000292.1; ENSLACP00000000290.1; ENSLACG00000000260.1.
DR eggNOG; ENOG502RV4W; Eukaryota.
DR GeneTree; ENSGT00940000159971; -.
DR HOGENOM; CLU_997335_0_0_1; -.
DR InParanoid; H2ZSB9; -.
DR OMA; QNLYFWH; -.
DR TreeFam; TF331549; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015321; TypeI_recpt_CBD.
DR PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23036:SF101; INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-2; 1.
DR Pfam; PF09240; IL6Ra-bind; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 145..238
FT /note="Type I cytokine receptor cytokine-binding"
FT /evidence="ECO:0000259|Pfam:PF09240"
SQ SEQUENCE 308 AA; 35776 MW; 8360BF9212619E58 CRC64;
LKLHRKITMV LIDFLYSGLQ KYIATYICFL FFTVVDPPTN LTIVDPGYLG KLYFQWKPPA
RLAGIPQCII WYKLQYRNTN IEKWKTVITK RLSHSDGFDL DEGVNVKVQT VLKGHCTNAS
EVQSEWIETT LWPSLLGDSE SKIHDLRCVV YNWEYMECLW QQNSIIPPNA NYQLYYWHKK
LNHAMQCTNY LQSNGVNVGC SFQSSELMGF TDFNICVTGS LDSMPLRSAY FTFELHNIVK
PAPPNQMKMN ITWPGEVTVT WTPSSGRIQP HCLEYEVQCN MLKKEGKRKK ETGQIVQNKM
FKIVYELP
//
