ID H2ZTF2_LATCH Unreviewed; 555 AA.
AC H2ZTF2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=DNA2/NAM7 helicase-like C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000000673.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000000673.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01229898; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01229899; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01229900; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01229901; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01229902; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01229903; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01229904; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2ZTF2; -.
DR STRING; 7897.ENSLACP00000000673; -.
DR Ensembl; ENSLACT00000000679.1; ENSLACP00000000673.1; ENSLACG00000000600.1.
DR eggNOG; KOG1802; Eukaryota.
DR GeneTree; ENSGT00940000162335; -.
DR HOGENOM; CLU_477827_0_0_1; -.
DR InParanoid; H2ZTF2; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF534; PROTEIN ZGRF1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 190..253
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 294..467
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 515..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 62343 MW; 724ADDEE336265AB CRC64;
RLSKGKFVPP AFNSRAVARS GLLSLTRTLE LAFEMIGKFC LNTGQAAALT QVAQMMAAGD
SPLEPGQQQI SPVTVVHGEL KRKSIVVFCL VLIFFFWNET NFFHTFVHPQ LVITKPNLLD
QQPKVALEVV LLLLLDLGFD KFIRVGSIRK ISKPILPYSL HAGMGSESEE LRELQSLLRE
DLTPVEKVYV RRSIEQHKLG SNKTLLGQVR VVGVTCAACP FPCMNKLKFP VVVLDECSQM
TEPSSLLPIA RQKCMTLWAI SKKKKNPPTV IQYSDMHLKN GIFFFFFSFF WLLGHQAVLL
RTQYRCHPAI SAIANDLFYE GRLLDGISEA DRSPLLDWLP TLCFYSVKGV EQIERDGSFY
NLQEATFTVK LIESLIASGT KGSMIGVITL YRSQMYKLCS LLAGAVHCDP AEVKAVQVST
VDAFQGAEKE IIVLSCVRTR QVGFIDSEKR MNVALTRGRR HLLIVGNLAC LRKNKLWGKV
IHHCEGRENG LKHASQSEQE LDGILRAYLE RRNEERNISN QKRKSRGKSL PLVQEVPDDS
QSTPVPADPR IVDWC
//
