ID H2ZU33_LATCH Unreviewed; 446 AA.
AC H2ZU33;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=F-box protein 3 {ECO:0000313|Ensembl:ENSLACP00000000904.2};
GN Name=FBXO3 {ECO:0000313|Ensembl:ENSLACP00000000904.2};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000000904.2, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000000904.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; AFYH01125674; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01125675; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01125676; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006002058.1; XM_006001996.2.
DR AlphaFoldDB; H2ZU33; -.
DR Ensembl; ENSLACT00000000913.2; ENSLACP00000000904.2; ENSLACG00000000811.2.
DR GeneID; 102345593; -.
DR KEGG; lcm:102345593; -.
DR CTD; 26273; -.
DR GeneTree; ENSGT00940000153571; -.
DR HOGENOM; CLU_056869_0_0_1; -.
DR OrthoDB; 5362121at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000000811; Expressed in pelvic fin and 6 other cell types or tissues.
DR CDD; cd22084; F-box_FBXO3; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.60.40.1470; ApaG domain; 1.
DR Gene3D; 3.40.1580.10; SMI1/KNR4-like; 1.
DR InterPro; IPR007474; ApaG_domain.
DR InterPro; IPR036767; ApaG_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR018958; Knr4/Smi1-like_dom.
DR InterPro; IPR037883; Knr4/Smi1-like_sf.
DR PANTHER; PTHR46550; F-BOX ONLY PROTEIN 3; 1.
DR PANTHER; PTHR46550:SF1; F-BOX ONLY PROTEIN 3; 1.
DR Pfam; PF04379; DUF525; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF09346; SMI1_KNR4; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00860; SMI1_KNR4; 1.
DR SUPFAM; SSF110069; ApaG-like; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF160631; SMI1/KNR4-like; 1.
DR PROSITE; PS51087; APAG; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 3..49
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT DOMAIN 272..402
FT /note="ApaG"
FT /evidence="ECO:0000259|PROSITE:PS51087"
SQ SEQUENCE 446 AA; 51078 MW; 1EEE252BF5130BC7 CRC64;
MAALQLVDLP ADPLLLIFSF LDFPDFFSCS CVNRRFNQLS SHDPLWKRHC QKYWLVSDRE
KAQRNQSWKD IFRAFLSNDL GQYIEHYATL KQAWEDLKRF LGQTCPRMIG SLKAGATEAE
LDAVEARIGC KLPADYRCSF RIHNGQKLVV PGLMGSMALS NHYRSEDLLD IDTAAEGFQQ
RAGLKQCLPL TFCIHTGLSQ YMALESVEGR ERQEIFYQCQ DQMAPNPSAI DMFLTGTSFT
DWFTSYVRSV IMGTYPIIRD QVFRYVHDKK CVATTGDITV SVSTSFLPEL SSIHPPHYFF
TYRIRIEMSK DALPKKACQL DSRYWRITDA NGDVENVQGP GVVGEFPILR PGNFYEYTSC
TTFLTTSGCM EGHYTFHRLL NEEEVFNVTI PRFHMVCLPF RVSVVCKEGN HKGSVYEEDS
TDTDDHEEVH RVLEFPVPGG HCPRHI
//
