ID H2ZWZ3_LATCH Unreviewed; 468 AA.
AC H2ZWZ3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000001914.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000001914.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR EMBL; AFYH01261990; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01261991; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01261992; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01261993; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2ZWZ3; -.
DR STRING; 7897.ENSLACP00000001914; -.
DR Ensembl; ENSLACT00000001928.1; ENSLACP00000001914.1; ENSLACG00000001711.1.
DR eggNOG; ENOG502QQ5W; Eukaryota.
DR GeneTree; ENSGT00940000164475; -.
DR HOGENOM; CLU_002555_11_2_1; -.
DR InParanoid; H2ZWZ3; -.
DR OMA; IDYCAHK; -.
DR TreeFam; TF329295; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 4.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR19331:SF22; DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN; 1.
DR PANTHER; PTHR19331; SCAVENGER RECEPTOR DOMAIN-CONTAINING; 1.
DR Pfam; PF00530; SRCR; 4.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 4.
DR SUPFAM; SSF56487; SRCR-like; 4.
DR PROSITE; PS00420; SRCR_1; 1.
DR PROSITE; PS50287; SRCR_2; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 1..90
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 117..222
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 251..356
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 367..467
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 15..79
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 28..89
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 59..69
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 147..211
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 160..221
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 191..201
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 281..345
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 294..355
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 392..456
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 405..466
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 436..446
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 468 AA; 50498 MW; 783930332A3B7C24 CRC64;
GRVEVYHNGE WGTVCDDGWG LEEAEVVCRE IGCGSAVSAP GSAAFGKGTG MIWLDDVVCT
PAAPSIFNCM AKTLGNANCG HIEDAGVVCS GKFYLHYKVM SSIIIKSKEC HSFSFKVYIF
MGERWNHFNQ CSGRVEVYHS GEWGTVCDDD WGMKDAEVVC RQIGCRSAVS APGSARFGQG
TGRIWLDDVA CTPAAASIFN CMGTPWGAHN CDHGEDAGVV CSGRPGEWRI WCPFIKRKLR
SQTYSVKEDK VRLMNGSATL LYHLCAGRVE VYHNDKWGTV CDDDWGLEEA EVVCREIGCG
SAVSAPGSAS YGQGTGTIWL DDVVSTATEA SIFNCTAKPW GNSNCNHEEE VFFWCILPCT
HEYLRSIILV NGPNQCSGRV EVYHSGEWGT VCDDDWGIED AQVVCTQIGC GSAVSAPGSA
RFGQGMGRIW LDDVACTPAT ASIFNCMVKS WGDHDCGHGE DAGVVCSG
//
