ID H2ZYH4_LATCH Unreviewed; 385 AA.
AC H2ZYH4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=ABC transmembrane type-1 domain-containing protein {ECO:0000259|PROSITE:PS50929};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000002445.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000002445.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01242722; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242723; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242724; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242727; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242728; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242729; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242730; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242731; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2ZYH4; -.
DR STRING; 7897.ENSLACP00000002445; -.
DR Ensembl; ENSLACT00000002465.1; ENSLACP00000002445.1; ENSLACG00000002183.1.
DR eggNOG; KOG0054; Eukaryota.
DR GeneTree; ENSGT00940000153931; -.
DR HOGENOM; CLU_000604_27_14_1; -.
DR InParanoid; H2ZYH4; -.
DR OMA; FIWEHES; -.
DR TreeFam; TF105202; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000002183; Expressed in muscle tissue and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR CDD; cd18593; ABC_6TM_MRP4_D1_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR030240; ABCC4_TMD1.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF357; ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 4; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 134..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..375
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
SQ SEQUENCE 385 AA; 44480 MW; 9922201CF8EFD7AF CRC64;
MEPVNKEEKP NPVAHANLFS KLFFCWLNPL LKIGHKRRLE EDDMYKVLPE DSSEILGEQL
QWYWDKEVFK AKKDLRVPHL TKAIMNCYWK SYSLLGAFTF LEESVKIIQP ILIGNLISYF
ESYDSNDIEA RNTAYGYAAG VSLCSLSLAI LHHLYFYHVQ RAGMKLRVAM CHMIYKKALC
LNHVALGKTT TGQIVNLLSN DVNKFDQVRF FLHFWLYSRD CRHPGSLLTA SGKRVVIGLH
WILLLIAVKV QTNDYYIIHR SKTAVFTDSR IKTMNEVISG IRIIKMYAWE KPFAELVHDI
RRKEISKILK SSYLRGMNLA SFFFSNKVIQ LVTFMTYVLL GNIVTASRVF VAVSLYNSVR
LTVALFFPLA IEKASESLVS IRRIK
//
