ID H2ZZW6_LATCH Unreviewed; 513 AA.
AC H2ZZW6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000002937.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000002937.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AFYH01042322; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042324; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01042327; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2ZZW6; -.
DR STRING; 7897.ENSLACP00000002937; -.
DR Ensembl; ENSLACT00000002962.1; ENSLACP00000002937.1; ENSLACG00000002628.1.
DR eggNOG; KOG1164; Eukaryota.
DR GeneTree; ENSGT00940000158111; -.
DR HOGENOM; CLU_019279_4_4_1; -.
DR InParanoid; H2ZZW6; -.
DR OMA; YCMVKWL; -.
DR TreeFam; TF106473; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000002628; Expressed in chordate pharynx and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR026870; Zinc_ribbon_dom.
DR PANTHER; PTHR11909; CASEIN KINASE-RELATED; 1.
DR PANTHER; PTHR11909:SF99; INACTIVE SERINE_THREONINE-PROTEIN KINASE VRK3; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13240; zinc_ribbon_2; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 212..496
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 64..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 58737 MW; 222DB36D033DC116 CRC64;
RMVNFCPECG QKMEITFTFC PYCGIQLPKA SAAEEAIPFS EIFPSTADEG TAYTYLFQTE
QVRKSHGTKQ SPMKTEGYKC SPKKRLPSSP KKNLEDVKSF QTSPISKLIS PGKQLSISTF
YSLLSYFVLL VVSFLSSQNY REHSFRLLRL YLFVLNVQSY PESLVSEHLT FKPINSNSFA
VRISPRVKRQ KTNAVEPLPE NAILMDTNNQ KWQLIELLTQ NDSGILYSEY KLTKCFGNCE
YSLKLNAKDG RLYNEQSFFQ RAAKLVKGND ISSSHQRPLL PVCNCIFFTM TPLFRFLVFR
KLGRSLHSIL SESGRPLSEK AVFQLSCRII DVLEYIHENE YVHADIKDEN IYVNPDDLNQ
VYLAGYSFAF RYCPGGKHVE YREGSRTPHE GTLEFTSLDS HKGAGPSRRS DLENLGYCMM
KWLFETLPWS DKIDNPSIVT EQKQRFKVDI PSFLKQCSGN RRIPGELEVY LKHVMALSYD
EKPNYTDLKN ILKIALQKIG GSSYDPVDLT SFP
//
