ID H3A0M7_LATCH Unreviewed; 286 AA.
AC H3A0M7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Tropomyosin alpha-1 chain {ECO:0000256|ARBA:ARBA00041188};
DE AltName: Full=Alpha-tropomyosin {ECO:0000256|ARBA:ARBA00042447};
DE AltName: Full=Tropomyosin-1 {ECO:0000256|ARBA:ARBA00042056};
GN Name=LOC102354886 {ECO:0000313|Ensembl:ENSLACP00000003198.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000003198.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000003198.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
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DR EMBL; AFYH01160967; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01160968; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01160969; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A0M7; -.
DR STRING; 7897.ENSLACP00000003198; -.
DR Ensembl; ENSLACT00000003228.1; ENSLACP00000003198.1; ENSLACG00000002856.1.
DR eggNOG; KOG1003; Eukaryota.
DR GeneTree; ENSGT01030000234542; -.
DR HOGENOM; CLU_055027_0_0_1; -.
DR InParanoid; H3A0M7; -.
DR OMA; LELEWEM; -.
DR TreeFam; TF351519; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000002856; Expressed in pectoral fin and 6 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 2.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR000533; Tropomyosin.
DR PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR PANTHER; PTHR19269:SF80; TROPOMYOSIN ALPHA-1 CHAIN; 1.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00326; TROPOMYOSIN; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT REGION 17..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 286 AA; 33142 MW; 13651979B27B8C9E CRC64;
EKMEAIKKKM QMLKLDKENA LDRAEQAETD MKGAEDRSKQ LEEELLGMQK KLKGTEDELD
KYSEALKDAQ EKLELAEKKA ADAEAEVASL NRRIQLIEEE LDRAQERLST ALLKLEEAEK
AADESERAMK VIETRSQRDE ERMELQEIQL KEAKFIAEEA DRKYEEVARK LVIIEGDLER
TEERAELAES KCAELEEELK NVTNSLKSLE AQAEKYSQKE DKYEEEIKIL SDKLKEAETR
AEFAERSVTK LEKTIDDLED ELYAQKLKYK AISEDLDHAL NDMTSM
//
