ID H3A1J3_LATCH Unreviewed; 224 AA.
AC H3A1J3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Twisted gastrulation BMP signaling modulator 1 {ECO:0008006|Google:ProtNLM};
GN Name=LOC102355095 {ECO:0000313|Ensembl:ENSLACP00000003514.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000003514.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000003514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the twisted gastrulation protein family.
CC {ECO:0000256|ARBA:ARBA00010047}.
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DR EMBL; AFYH01242006; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01242007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A1J3; -.
DR STRING; 7897.ENSLACP00000003514; -.
DR Ensembl; ENSLACT00000003545.1; ENSLACP00000003514.1; ENSLACG00000003134.2.
DR eggNOG; ENOG502RZVM; Eukaryota.
DR GeneTree; ENSGT00390000007058; -.
DR InParanoid; H3A1J3; -.
DR OMA; EVCQCEA; -.
DR TreeFam; TF323922; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000003134; Expressed in pelvic fin.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR006761; Tsg.
DR PANTHER; PTHR12312:SF16; TWISTED GASTRULATION PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR12312; TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED; 1.
DR Pfam; PF04668; Tsg; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..224
FT /note="Twisted gastrulation BMP signaling modulator 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003579779"
SQ SEQUENCE 224 AA; 24612 MW; 69BF3B926F675568 CRC64;
RMYRPVTFLL LASSCGLISA VIGCNKALCA SDVSKCLLQE LCQCQVNEAG CPCCRECMLC
LATLWDQCCD CVERCDVCMY VCAVRTLKAA VLDLLVPIPS LFRALTTISD NDPPMGWSVV
SIPVTEELRH QHHRHHIMLG SHKGHHTGEI IAVAELLPGS SENSTAVCTV LYFHSCMSMN
RCKQSCESLG ASRYRWFHNA CCECVGPDCH AYGSKEAACQ NCNI
//
