ID H3A273_LATCH Unreviewed; 300 AA.
AC H3A273;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Palmitoyl-protein thioesterase 2 {ECO:0000313|Ensembl:ENSLACP00000003744.1};
GN Name=PPT2 {ECO:0000313|Ensembl:ENSLACP00000003744.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000003744.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000003744.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the palmitoyl-protein thioesterase family.
CC {ECO:0000256|ARBA:ARBA00010758}.
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DR EMBL; AFYH01180322; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006007241.1; XM_006007179.2.
DR AlphaFoldDB; H3A273; -.
DR STRING; 7897.ENSLACP00000003744; -.
DR Ensembl; ENSLACT00000003778.1; ENSLACP00000003744.1; ENSLACG00000003336.1.
DR GeneID; 102355870; -.
DR KEGG; lcm:102355870; -.
DR CTD; 100126133; -.
DR eggNOG; KOG2541; Eukaryota.
DR GeneTree; ENSGT00940000155779; -.
DR HOGENOM; CLU_050129_1_0_1; -.
DR InParanoid; H3A273; -.
DR OMA; EEHNVDS; -.
DR OrthoDB; 5471876at2759; -.
DR TreeFam; TF323926; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000003336; Expressed in chordate pharynx and 4 other cell types or tissues.
DR GO; GO:0098599; F:palmitoyl hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002472; Palm_thioest.
DR PANTHER; PTHR11247:SF27; LYSOSOMAL THIOESTERASE PPT2; 1.
DR PANTHER; PTHR11247; PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1; 1.
DR Pfam; PF02089; Palm_thioest; 1.
DR PRINTS; PR00414; PPTHIESTRASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..300
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003579493"
SQ SEQUENCE 300 AA; 34007 MW; F8E2E097E36AB902 CRC64;
MVRLGRLQPG GVLPLLPLLL LFAGGLLLPP ASGYKPVVIV HGLFDSPSDF KHMLSFINQT
HPGTNVTVID LYDHTLSLLP MWKQVEGFRN AIYPIMQNAA EGLHLMCYSQ GGLICRALLS
MIPDHNVDTF ISLSSPQLGQ YGDTVYLKWI FPHYVKSNLY KLCYTHLGQD FSICNYWKDP
HHQDLYQNTS DFLALLNSER FNPSAAEWRK NFLRLRNLVL IGGRDDGVIT PWQSSHFGFY
NANETVVEMK KQMVYLRDAF GLKSLDARGA ITTYAVDGVQ HTNWHSNQTV FEACIAKWLT
//
