ID   H3A2I3_LATCH            Unreviewed;      1102 AA.
AC   H3A2I3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=SEA domain-containing protein {ECO:0000259|PROSITE:PS50024};
GN   Name=LOC102359917 {ECO:0000313|Ensembl:ENSLACP00000003854.1};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000003854.1, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000003854.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AFYH01208264; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01208265; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01208266; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01208267; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7897.ENSLACP00000003854; -.
DR   Ensembl; ENSLACT00000003889.1; ENSLACP00000003854.1; ENSLACG00000003431.1.
DR   eggNOG; ENOG502S1MW; Eukaryota.
DR   GeneTree; ENSGT00940000166494; -.
DR   HOGENOM; CLU_267028_0_0_1; -.
DR   InParanoid; H3A2I3; -.
DR   OMA; LIAYENC; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000082; SEA_dom.
DR   InterPro; IPR036364; SEA_dom_sf.
DR   PANTHER; PTHR37999; MUCIN-17; 1.
DR   PANTHER; PTHR37999:SF2; MUCIN-17; 1.
DR   Pfam; PF01390; SEA; 1.
DR   SMART; SM00200; SEA; 1.
DR   SUPFAM; SSF82671; SEA domain; 1.
DR   PROSITE; PS50024; SEA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1004..1029
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          803..918
FT                   /note="SEA"
FT                   /evidence="ECO:0000259|PROSITE:PS50024"
FT   REGION          1..442
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          475..714
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1076..1098
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        475..694
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        695..709
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1102 AA;  113430 MW;  5B585472709AF072 CRC64;
     TSTTPSDTDS TVETTTVTEG SSSTYISTSG TVSTTESSIT TEESSPTSTA PSDTESTVQS
     STVTDSSSST YISTSEAVST TESSIASEES SPTSTTPSDT DSTVETTTVT EGSSSTSIPT
     SGTVSTTESS TPTEESSPSS KAPSGTESIV QSSTVTDGSS STYISTSGAV STTESSTPTE
     ESRRTSTAPS ALVSTVETTT VTEGSSSTYI STSGALSTTE SFTPIEESSP TSTAPSGTES
     IVQSSTVTDS SSSTSISTSG AVSTTESSTP TAESSSTSTA PSVTVNTVQT AAVIEGSSST
     SISTSRAVST TESSTPTEES SPTSTAPRGT VSTVQTAAVI EGSSSTSIST SRAVSTTELS
     ITTEESSPTS TTPSDTDSTV ETTTVTEGSS STYISTSGAV STTESSTPID ESSPTNIAPN
     GTESTAETSA VTGGPFPTYT STSVSVGTAE TITVTESLST NYTSTRATES TIEISTVAGG
     PSPTYTSTSE SVGTVETSMV TNGSLPATTT SDSRATSVGL GVHPPSTTTE PSGTTSWEPE
     LESSPSSSPS SSVTISSTPM SPSSSTPAIS NSSMNTPANS SSPALTPTSP SSTAPTTTPT
     SASTVPEGTT NASSPTSPSS TAPTTXTTTP TSASTVPEGT TNASSPTSPS STAPTTTLTS
     ASTVLEGTTN ASSPTSPSST APPTTKIMTT TPTPTTTPTT PPTTTTIPTT MPPKVPGSFS
     TKIFQSTLLL KSGSQTDFTL HSYASCLVPP VPHPVIMCFF AVLGMTCENG GTYDGIKCNC
     DETYYYGPHC EFAVEAVTIV PPPTETYNRT VDVTARITNE KLTENLKDTS TVEYKTFSTN
     FKQQMFKLYK GVDGYKDVDI ISLTEGSIIV DYKVILEIKA VAAGEEKNDR YKDAVNNITS
     IMMSTTCTKN ETGTVLTLRK NFWLGRPNNL CKSLGDLIQF YELYIDEKDA VSCISICNSL
     AKGFVNCTKN GKCELLNSGP SCFCLSTEEY LYTGSHCKIV INKYGLYGGI AAALLVLVIV
     ITTLTVFVIR RKGKQQKEWD SKQDLVDKWF DDDVEWHAPE GFTVARPESV NWEGLESRES
     ASGTGSSNFT PSLTNVNTTV EV
//