ID H3A4R1_LATCH Unreviewed; 1011 AA.
AC H3A4R1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Sperm antigen with calponin homology and coiled-coil domains 1 {ECO:0000313|Ensembl:ENSLACP00000004632.1};
GN Name=SPECC1 {ECO:0000313|Ensembl:ENSLACP00000004632.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000004632.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000004632.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01104056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104057; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104059; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104060; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104061; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104064; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01104065; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A4R1; -.
DR Ensembl; ENSLACT00000004671.1; ENSLACP00000004632.1; ENSLACG00000004123.2.
DR GeneTree; ENSGT00940000153592; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000004123; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF3; CYTOSPIN-B; 1.
DR Pfam; PF00307; CH; 1.
DR SMART; SM00033; CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 905..1010
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 21..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 116..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 294..467
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 57..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..714
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..735
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1011 AA; 113134 MW; 3B95EA297D3600D9 CRC64;
MKKTVTAGAI SELAEGRIKH GAGPVASGKR TGIPVPRELP AAVSRDKPFL RGPSVTKKGA
SSPTSSNVTT PTKYVRTAIK PKQESEANGK TMLESQVKEL LAEAKTKDFE ISSLRSELKK
CRDKGSPNSE TPGQESGNLL AQPAEEESLI KGLKEKNWTF QHELAVLREE NQVLKEKLIA
LEYSPSLETS TSNSTNSNLP TPSTQESSFG SPLKSPVNGD LYDKSRVTVN GGKLRSPSSS
SSDVTKVSPS SDTSEFENIA DVSSRTDSSN SISFKGSKCS TTGNSPGDVS ELSVACLTEK
IQKMEETHHS TAEELQATLQ ELSDQQQMVQ ELTADNERFV EEKAMLESSL HQQRERVEQL
VQENENLMAL LKERAKTEET EVKEKRVLEL EQRYDELIER SRFEREKLLN IQQQFTSSLR
SLEKEHQEAQ GLIKSLKEEN SHLQRLLESE QQAKNEMAKA IEDYKSMVEG SNLENGHLKA
QLEMQKQAAV EYRAGQGSGE TLELLNVSQL DKEQLCVAYT ELKQKFSKAN GEVRQLQGML
EKMEAECRQL KELCDKQAEE LNSSSLKREE ESSETEAEIK HMKEAIFELE DQVEQHRAVR
LHNNQMMIDL ENNVLALEEQ KLDLEKQLKA LNRQMKEDAE EWRRFQADLQ TAVVVANEIK
IEAQQEVRAL RKRLHEEEEQ NLALQKEMDE LKGNRDDDEN ETGITLDKLT EEDAGNQWHG
VSASRTSPVP SEPSTTVKSL IKSFDAGFQE GSSQPVQIHT VPRSPLSGIP VRTAPAAAVS
PMQRHASSSS VKLISKAPEK RAHFAEFPMT AFAFWTSHME HSIILPESVP LPASKVIYML
KGRSNDLKPE QYLRKSPSLE SIGKAPSIAV SSRSLAMTSS HPKLQSRLSV ERMDPLTALA
RAYGGSKRNA LLKWCQQKTE GYQNIDITNF SSSWSDGLAF CALLHTYLPA HIPYQELSSQ
DKKRNLMLAF QAAESVGIKP ALEITDMVNT DRPNWQSVMQ YIAQIYKYFE T
//
