ID   H3A554_LATCH            Unreviewed;       580 AA.
AC   H3A554;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=HAT C-terminal dimerisation domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000004775.1, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000004775.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AFYH01079199; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H3A554; -.
DR   Ensembl; ENSLACT00000004816.1; ENSLACP00000004775.1; ENSLACG00000004244.1.
DR   eggNOG; ENOG502QSU3; Eukaryota.
DR   GeneTree; ENSGT00940000162068; -.
DR   HOGENOM; CLU_006175_4_2_1; -.
DR   InParanoid; H3A554; -.
DR   OMA; LNDLMCG; -.
DR   TreeFam; TF330114; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR025398; DUF4371.
DR   InterPro; IPR008906; HATC_C_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   PANTHER; PTHR45749; -; 1.
DR   PANTHER; PTHR45749:SF29; DIMER_TNP_HAT DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR   Pfam; PF14291; DUF4371; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   DOMAIN          39..222
FT                   /note="DUF4371"
FT                   /evidence="ECO:0000259|Pfam:PF14291"
FT   DOMAIN          504..553
FT                   /note="HAT C-terminal dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF05699"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   580 AA;  66201 MW;  B84FCE168E9A547C CRC64;
     VEGYKTGKNS VESFRQHEKN KSHRETTTQF QTQISKQPSI ATQLDSQLRA QQNYRCEMLL
     KQPTSLRYLM SQGVAVEGHD AHNGYLFQLL QPRAEDCPDL CQWLNDKNYM SHDINNELIQ
     LISLDILQRL LEKIHEAGFY SILADETCDT VNKKQLVVLF HWVDEEYTIH EDFIGLVDLP
     QTDSATIYSV LNDILIRCNI PPGLCRGQAY DSASNMSGHI RGVAARFKQQ NPAAIHIHCL
     AHCTNLCLQD VSKKNPKLEN SLSYMIDALK AILDNYSVLC AAMTETNNDS HDEYGRRAGG
     ILAMLDKLDT FYGLCLSYLV FSATEQLSRT LQAVNTSLHN ARNAVQLTSG NLQNRPAKHS
     TTEDARDLTA APVLPRHHRP PIRIDEGEKK KNHTFQSPES FYRKQYYKLL DLLDNELAWR
     FEQKDTIVAS DIEQLLLTSA NEETIKFPTT TLETYSNDFD RLHTQLLMMP ETLKESAKGN
     KIKKVTSIRT ISDAMNVVLV SKRLLPEVHK LLRLHYTVPV TTATAERCFS SLRRIKNYLQ
     SKMTQKRLND LMCGYCHKEA LSETDMTSTT SEFAQRNTEF
//