ID H3A5K4_LATCH Unreviewed; 350 AA.
AC H3A5K4;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=LOC102348567 {ECO:0000313|Ensembl:ENSLACP00000004925.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000004925.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000004925.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|RuleBase:RU004439}.
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DR EMBL; AFYH01253576; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A5K4; -.
DR STRING; 7897.ENSLACP00000004925; -.
DR Ensembl; ENSLACT00000004968.1; ENSLACP00000004925.1; ENSLACG00000004379.1.
DR eggNOG; ENOG502RQEK; Eukaryota.
DR GeneTree; ENSGT01100000263475; -.
DR HOGENOM; CLU_047501_0_0_1; -.
DR InParanoid; H3A5K4; -.
DR OMA; PEISMMW; -.
DR TreeFam; TF352056; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd21029; IgC1_CD1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675:SF235; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP BETA 1 CHAIN-LIKE [PROVISIONAL]; 1.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 315..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..305
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 350 AA; 40315 MW; CC3F61DEB1C3BEEF CRC64;
IISLLFFPAE SALLCNLHTL QEILSLSLSQ SRRSESLRYF YTAARTVGLP DLPEFMAVGY
MDEVLLGEYN SWSGKAVSRQ HWMQEYSQAE EPQFWERMTQ LAKEHQASFK VNIQILMHIY
NQTSGVHTYQ RRYGCELRDD ATTGGFDQFG YDGEDFISFD KEKLIWVAAV DQAIPSQDNW
NANTAFIQGT KTYLEEECIE FLKKLIRYGN KTLERKVCPE VTVYDRPDFE SESIILTCMA
TGFHPRSIDV SWVRDENTQM NDVYTDGILP NEDGTFQIKM TLQIDLKDKR SYACHVDHSS
LEEIMKVPWV LSNVLATWII IVIVIVVVGT VLVAAVVGFV IWRRKKRGKK
//
