ID H3A692_LATCH Unreviewed; 133 AA.
AC H3A692;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Astrocytic phosphoprotein PEA-15 {ECO:0000256|ARBA:ARBA00015367};
DE AltName: Full=15 kDa phosphoprotein enriched in astrocytes {ECO:0000256|ARBA:ARBA00033278};
GN Name=PEA15 {ECO:0000313|Ensembl:ENSLACP00000005163.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000005163.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000005163.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AFYH01124703; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124706; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124709; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124710; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124711; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01124712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A692; -.
DR STRING; 7897.ENSLACP00000005163; -.
DR Ensembl; ENSLACT00000005209.1; ENSLACP00000005163.1; ENSLACG00000004587.2.
DR eggNOG; KOG3573; Eukaryota.
DR GeneTree; ENSGT00390000000230; -.
DR InParanoid; H3A692; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000004587; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0000165; P:MAPK cascade; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd08338; DED_PEA15; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001875; DED_dom.
DR InterPro; IPR029546; PEA15_DED.
DR PANTHER; PTHR48169:SF1; ASTROCYTIC PHOSPHOPROTEIN PEA-15; 1.
DR PANTHER; PTHR48169; DED DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01335; DED; 1.
DR SMART; SM00031; DED; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50168; DED; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 6..84
FT /note="DED"
FT /evidence="ECO:0000259|PROSITE:PS50168"
SQ SEQUENCE 133 AA; 15644 MW; 737B6739501B10CD CRC64;
PQKMAEYNAL LDDLMDNITN EDLEQLKSAC KEDIPSDKSE EITCSKEWFN FLEKHEKLSK
DNLSYIEHIF EISRRPDLLT MVIDYRTKVL KISEDEEIDT KLTRIPSAKK YKVFLFPPTR
NSIPPLVPPQ FDH
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