ID H3A7C1_LATCH Unreviewed; 869 AA.
AC H3A7C1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Olfactory receptor C family, w1 {ECO:0000313|Ensembl:ENSLACP00000005542.1};
GN Name=LOC102360458 {ECO:0000313|Ensembl:ENSLACP00000005542.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000005542.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000005542.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AFYH01233562; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A7C1; -.
DR Ensembl; ENSLACT00000005591.1; ENSLACP00000005542.1; ENSLACG00000004927.1.
DR eggNOG; KOG1056; Eukaryota.
DR GeneTree; ENSGT01100000263565; -.
DR HOGENOM; CLU_005389_5_1_1; -.
DR InParanoid; H3A7C1; -.
DR OMA; AVWIAYI; -.
DR TreeFam; TF331269; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06364; PBP1_CaSR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF0; VOMERONASAL 2, RECEPTOR 23-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00592; CASENSINGR.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..869
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003580001"
FT TRANSMEM 608..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 722..746
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 766..790
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 802..822
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 834..858
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 608..869
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 869 AA; 97449 MW; 17AE2503336873F9 CRC64;
QKFFSWHIKM YLIISLCLFS TRQMPSEGSE PPCNRLTRFG VQGFYKTGEI ILGGLFPMHS
RVINQELSFN VSPNITHCEG FDFRTFRWLQ VMFFTLEEIN NSTELLPNIT LGYIVYDTCA
TSNQALRAAL SLASGPDNFE TIDECGDSPL IPVILGDSGS TQSMALAKVL SPFRIPMVSY
FASCAYLSNQ EQFPIFFRTI PSDFYQARAL AKLVQRFGWT WVGAIGADDD YGRDGVQSFN
NEVKKFGACV AFKEIIPKVT SKVQILRIVK TIKRSTAKVI VLFAIEADAY PLLQELALQN
ITDKQWIASE AWVTSALIST DKSLSFLAGT IGFAIRRAEM PELKDFLLKV HPLRQSQNMF
TREFWETLFE CSFQSSSNIT GELEPTASNE TCTGLENFDE KDSIYSDITQ LRVSYNIYKA
IYAIVHALHN LYSCTDGEGP FAFNSCANIF SLQPWQVLHY LTEVRFTDKF GQETYFDENG
DPVGSYDILN WQKDITDAIQ YVQIGDFDAS AEIGMDLVID EQKIIWSGGQ TKVPRSVCTE
SCQPGTRKTA RVGQSVCCFD CLPCADGEIS NETDAVKCIQ CSLDYWPNGK KDKCILKEIE
FLSFHDTLGI TLTIVSLVGA LTTLTVASVF LQYKTTPIVR ANNSELSFLL LFSLILCFLC
SLSFIGRPTV WSCMLRHTLF GISFVLCISC VLGKTIVVLM AFKATLPGNN VMQYFGPTQQ
RLIVSLCTLI QVTFCIVWVT VLPPIPYKNS SHYSYKIILE CALGSLALYG CVMGYIGFLS
CICFILAFFA RKLPDNFNEA KFITFSLIIF CAVWITFIPA YISSPGKYTV AVEVFAILSS
SFGLLLCIFA PKCYVILLKP EKNTKKHMM
//
