ID H3A802_LATCH Unreviewed; 772 AA.
AC H3A802;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Semaphorin 3F {ECO:0000313|Ensembl:ENSLACP00000005773.1};
GN Name=SEMA3F {ECO:0000313|Ensembl:ENSLACP00000005773.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000005773.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000005773.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; AFYH01072418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072419; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072420; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072422; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072425; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072426; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01072427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A802; -.
DR STRING; 7897.ENSLACP00000005773; -.
DR Ensembl; ENSLACT00000005823.1; ENSLACP00000005773.1; ENSLACG00000005125.1.
DR eggNOG; KOG3611; Eukaryota.
DR GeneTree; ENSGT00940000156703; -.
DR HOGENOM; CLU_009051_5_0_1; -.
DR InParanoid; H3A802; -.
DR OMA; HQDYIFY; -.
DR TreeFam; TF352628; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000005125; Expressed in muscle tissue and 3 other cell types or tissues.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd05871; Ig_Sema3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF27; SEMAPHORIN-3F; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..772
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003579035"
FT DOMAIN 31..523
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 596..668
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 557..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 748..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 86753 MW; 809FDF44F50DD1B0 CRC64;
MSFLELAFSL CLLALSLWTS SGKGQPPAAP RVQLNFKELK GTGTARYFSF FLNTTDYRIL
LMDEDHDRMY VGSKDHLLSL DLQDINREPL IGECGNFIRL IEPWNRTHLY VCGTGAYNPI
CTYVNRGRKP QVSDLTQLPL VGGRASRAAD LSTTPAPVDQ KEYIFSLEPG TSESGKGKCS
YDPKLNSVSA LINGELYAGV YIDFMGTDAA IFQTMGKQTA MRTDQYNSRW LNDPAFVHAQ
LIPDSAERND DKLYFFFREK ASDAGQSPVI HSRIGRICLN DDGGHCCLVN KWSTFLKARL
ICSVPGPDGI ETHFDELQDV FIQQTQDVKN PVIYAVFSAS GSVFKGSAVC VYSMADIRMV
FNGPFAHKEG PNYQWMPYTG KIPYPRPGTC PGGTFTPFMK STKDYPDEVI NFMRNHPTMY
NAVYPVHRRP LVVRTNVDYE FTTIAVDQVD AADGRYEVLF LGTDHGTVQK VIVLPKDDLE
TEELILEEVE VFKAPVPIST MRISTKRQQL YLTSSLGVTH MALHRCDVYG KVCADCCLAR
DPYCAWDGKS CSRYSASSKR RSRRQDVRHG NPIRQCRGYN SNANKNTVEL VQYGVEGSST
FLECPPRSPQ ATIKWLLQRD NSDRKREMKS DQRVLKTEQG LLLRNLQASD SGFYHCTATE
NNFKHTVALV QLHVLNSETV SAVLFQTEVP LPLPAAGLQA GSPGTFQTPH PQYKDLLQIL
SQPEMGLINQ YCQDYWQVSA SSQKDMLGSL KAKEQKKARN RRNHHEHSGQ QT
//
