ID H3A8H7_LATCH Unreviewed; 280 AA.
AC H3A8H7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};
GN Name=ATP1B3 {ECO:0000313|Ensembl:ENSLACP00000005948.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000005948.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000005948.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: This is the non-catalytic component of the active enzyme,
CC which catalyzes the hydrolysis of ATP coupled with the exchange of
CC Na(+) and K(+) ions across the plasma membrane.
CC {ECO:0000256|RuleBase:RU362099}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta family.
CC {ECO:0000256|ARBA:ARBA00005876, ECO:0000256|RuleBase:RU362099}.
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DR EMBL; AFYH01135213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01135214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01135215; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01135216; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006002830.1; XM_006002768.2.
DR AlphaFoldDB; H3A8H7; -.
DR STRING; 7897.ENSLACP00000005948; -.
DR Ensembl; ENSLACT00000006000.1; ENSLACP00000005948.1; ENSLACG00000005279.1.
DR GeneID; 102349197; -.
DR KEGG; lcm:102349197; -.
DR CTD; 30468; -.
DR eggNOG; KOG3927; Eukaryota.
DR GeneTree; ENSGT01030000234579; -.
DR HOGENOM; CLU_057702_1_1_1; -.
DR InParanoid; H3A8H7; -.
DR OMA; AHENYVQ; -.
DR OrthoDB; 2880589at2759; -.
DR TreeFam; TF314618; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000005279; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR Gene3D; 2.60.40.1660; Na, k-atpase alpha subunit; 1.
DR InterPro; IPR000402; Na/K_ATPase_sub_beta.
DR InterPro; IPR038702; Na/K_ATPase_sub_beta_sf.
DR NCBIfam; TIGR01107; Na_K_ATPase_bet; 1.
DR PANTHER; PTHR11523; SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT; 1.
DR PANTHER; PTHR11523:SF47; SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3; 1.
DR Pfam; PF00287; Na_K-ATPase; 1.
DR PROSITE; PS00391; ATPASE_NA_K_BETA_2; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362099};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362099};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362099};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362099}; Transport {ECO:0000256|RuleBase:RU362099}.
FT TRANSMEM 39..63
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362099"
SQ SEQUENCE 280 AA; 31856 MW; 5D286EE4CC04075A CRC64;
MAVKEEKKSF GHSIASFGRF LYNGQTGEVL GRRARSWGLI LLFYLVFYVF LAGLFVLTLW
VMLQTLDEYT PKYRDRISSP GLMIRPKVSG LNIAFNFSDP ASFENYVDVL HKFLKPYNDS
EQSNNKACDQ GIYFEQDSAV EKKACQFNRS VLEQCSGVND DTFGYSRGNP CVFVKMNRII
GLKPIGNPHV ICSLKEGENL TMLYFPAKGN IDLMYFPYYG KIAQIHYVQP LVAVKLMVSP
TNIGKELTIT CKIDGSKNLK NTDERDRFLG RVTFKVHVTK
//
