ID H3A975_LATCH Unreviewed; 422 AA.
AC H3A975;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=IPT/TIG domain-containing protein {ECO:0000259|SMART:SM00429};
GN Name=LOC102366753 {ECO:0000313|Ensembl:ENSLACP00000006196.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000006196.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000006196.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|ARBA:ARBA00010340,
CC ECO:0000256|RuleBase:RU004489}.
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DR EMBL; AFYH01231033; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01231034; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3A975; -.
DR STRING; 7897.ENSLACP00000006196; -.
DR Ensembl; ENSLACT00000006248.1; ENSLACP00000006196.1; ENSLACG00000005494.1.
DR eggNOG; KOG3836; Eukaryota.
DR GeneTree; ENSGT00950000182859; -.
DR HOGENOM; CLU_016320_3_0_1; -.
DR InParanoid; H3A975; -.
DR OMA; RFVYVCE; -.
DR TreeFam; TF313391; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000005494; Expressed in pharyngeal gill and 5 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01175; IPT_COE; 1.
DR Gene3D; 1.10.287.4280; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.3180; Transcription factor COE1, DNA-binding domain; 1.
DR InterPro; IPR032200; COE_DBD.
DR InterPro; IPR038173; COE_DBD_sf.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR038006; COE_IPT.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR003523; Transcription_factor_COE.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF4; TRANSCRIPTION FACTOR COE3; 1.
DR Pfam; PF16422; COE1_DBD; 1.
DR Pfam; PF16423; COE1_HLH; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004489}; Nucleus {ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 78..162
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REGION 267..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 45465 MW; B454D7A3AB0AFF4A CRC64;
RFFLKFFLKC NQNCLKNAGN PRDMRRFQVV VSTTVNVDGH VLAVSDNMFV HNNSKHGRRA
RRLDPSEGTA PYLENAATPC IKAISPSEGW TTGGATVIII GDNFFDGLQV VFGTMLVWSE
LITPHAIRVQ TPPRHIPGVV EVTLSYKSKQ FCKGAPGRFV YTALNEPTID YGFQRLQKVI
PRHPGDPERL PKEVLLKRAA DLVEALYGMP HNNQEIILKR AADIAEALYS VPRNHNQIPA
LANTPTHTGM MGVNSFSSQL AVNVSETSQA NDQVGYSRNT SSVSPRGYVP SSTPQQSNYN
TVSNSMNGYG NAGMPNLGVP GSPGFLNGSS ANSPYGIVPS SPTMAASSVT LPSNCSSTHG
IFSFSPANVI SAVKQKSAFA PVVRPQASPP PSCTSANGNG LQGELRSLIS FSSFFSDHLQ
RS
//
