ID   H3ABX3_LATCH            Unreviewed;       488 AA.
AC   H3ABX3;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000007144.1, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000007144.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AFYH01096752; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H3ABX3; -.
DR   STRING; 7897.ENSLACP00000007144; -.
DR   Ensembl; ENSLACT00000007203.1; ENSLACP00000007144.1; ENSLACG00000006339.1.
DR   eggNOG; ENOG502QTJW; Eukaryota.
DR   GeneTree; ENSGT01100000263476; -.
DR   HOGENOM; CLU_002274_3_2_1; -.
DR   InParanoid; H3ABX3; -.
DR   OMA; WASEKCC; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR   PANTHER; PTHR45690:SF15; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   DOMAIN          17..148
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   488 AA;  55468 MW;  16E6587C561A9E90 CRC64;
     IMENIFPLEK SGTQAPKTIM LKGISGIGKT IVTQKIIYDW ASEKCCKQFY CVLSFHFQEL
     NLIRWPISLK NLILEKYGEL APVLPELLQK PNILITLDGL DEFKHQLDFH GSKVYKSVDD
     VATVAEIVVN LLNQNLLPKA TIFLTTRPTV SSVPKKLIDK NLVLAGFTSS GTKEYCLNYY
     KDIRIAGIVY NYISGYDSLS ALSFIPLYCY IICTLVEKIV TKGKDQLPSY RPPLTVTEVY
     HQYLINALQH HGRGTEVPSQ QDPSQVIGIS VKQAIFRLGK LAYKGLLSNM ILFDEEMLNY
     YGLSLNSLPS SFLTNVFTTQ QYGEQCLYSF FHVTLQEFFA ALYCVIEIGD NDQTLIECLN
     AWCLGEVHQS GNIHLLEDIT QDSGNLQEQL QTFTKFFVGL LKLIKDKSLT GLIESNNDNI
     LFLLKKWFTV CFEDETLTKH HFLILANCLF EFQEYSIVKS TSPNINEIQL ENIKLFPLDC
     VAINYALK
//