ID H3ACB5_LATCH Unreviewed; 440 AA.
AC H3ACB5;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Septin {ECO:0000256|PIRNR:PIRNR006698};
GN Name=SEPTIN11 {ECO:0000313|Ensembl:ENSLACP00000007286.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000007286.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000007286.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, axon
CC {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendritic spine
CC {ECO:0000256|ARBA:ARBA00004552}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|PIRNR:PIRNR006698, ECO:0000256|RuleBase:RU004560}.
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DR EMBL; AFYH01220493; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220494; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220496; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220497; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220498; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220499; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220500; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220501; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01220502; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ACB5; -.
DR STRING; 7897.ENSLACP00000007286; -.
DR Ensembl; ENSLACT00000007346.1; ENSLACP00000007286.1; ENSLACG00000006461.1.
DR eggNOG; KOG3859; Eukaryota.
DR GeneTree; ENSGT00940000160196; -.
DR InParanoid; H3ACB5; -.
DR OMA; INQQFEN; -.
DR TreeFam; TF101080; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000006461; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0030424; C:axon; IEA:UniProtKB-SubCell.
DR GO; GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF48; SEPTIN-11; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 41..307
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT REGION 374..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 50946 MW; 7F7CAC9D2059BE92 CRC64;
FKNNHLFCLK SQSEDMRNLG LSGHVGFDSL PDQLVNKSTT QGFCFNILCV GETGIGKSTL
MDTLFNTKFE SDPASHKEPG VRLKAQSYEL QESNVRLKLT IVDTVGFGDQ INKEDSYKPI
VEYIDTQFEA YLQEELKIKR SLYNYHDTRI HACLYFIAPT GHSLKSLDLV TMKKLDSKVN
IIPIIAKADT IAKNELHKFK SKIMSELVSN GVQIYQFPTD EETVAEINAT MSVHLPFAVV
GSTEEVKIGN KMAKARQYPW GVVQVENENH CDFVKLREML IRVNMEDLRE QTHTRHYELY
RRCKLEEMGF KDSDPDSKPF SLQETYEAKR NEFLSELQKK EEEMRQMFVM RVKEKEAELK
EAEKDLHEKF EHLKKTHQDE KKKLEDKKKD LEEEMNAFSK KKAATQLLQS QAQQAGSQQT
KKDKDKKNQR TVLTVIQLLQ
//
