ID H3ADI0_LATCH Unreviewed; 149 AA.
AC H3ADI0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000007701.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000007701.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FAM13 family.
CC {ECO:0000256|ARBA:ARBA00007549}.
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DR EMBL; AFYH01157701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157702; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157703; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157706; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01157708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ADI0; -.
DR Ensembl; ENSLACT00000007765.1; ENSLACP00000007701.1; ENSLACG00000006822.1.
DR GeneTree; ENSGT00950000183033; -.
DR HOGENOM; CLU_015883_3_2_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR039102; FAM13.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15904; FAM13; 1.
DR PANTHER; PTHR15904:SF18; PROTEIN FAM13A; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 42..149
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 149 AA; 16625 MW; 4AD807BB731A455B CRC64;
SLLLCSFQQN KAAVRLREDM KKVVSQPLVK QKSLSYRKVF GVSLPDLQQQ GLVKEGVPAV
LWHMVEYLKE TGLKQEGLFR VNGSVKVVEQ LRLKLESGEE AELIKDGDVC SVASLLKLFL
RELPDGVITS ALHPKFMQLY QACHLGASC
//
