ID H3AFB7_LATCH Unreviewed; 779 AA.
AC H3AFB7;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=PHD finger protein 14 {ECO:0000313|Ensembl:ENSLACP00000008338.1};
GN Name=PHF14 {ECO:0000313|Ensembl:ENSLACP00000008338.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000008338.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000008338.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01165770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165771; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165772; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165773; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165775; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165776; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01165779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AFB7; -.
DR Ensembl; ENSLACT00000008404.1; ENSLACP00000008338.1; ENSLACG00000007379.2.
DR GeneTree; ENSGT00940000156923; -.
DR HOGENOM; CLU_006506_0_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000007379; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15674; ePHD_PHF14; 1.
DR CDD; cd15561; PHD1_PHF14; 1.
DR CDD; cd15562; PHD2_PHF14; 1.
DR Gene3D; 2.30.30.1150; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF150; PHD FINGER PROTEIN 14; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 206..267
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 269..391
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 617..671
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 716..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 522..570
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..766
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 779 AA; 87831 MW; 86126F4665726E51 CRC64;
DSEGSGNGSD DGSKESGEGS TSESEENTLE GETEGQQQGD KEPQKSPVVE GTSGNEEKTE
DQSVKSENKD ENDSKSKKKK DKMPEPDAGI GTEDSATEPK KWNLRRNRPL LDFITMEDLN
EIDDYDSEDD NDWRPAPGKK KGKKENDSSA SEDEKKKKKA NPSTRNSADD EELTNDSLTL
SQGKSNEDSL ILDKSQNWNA QKMDHILICC VCLGDNSEDA DEIIQCDNCG VTVHEGCYGV
DGESDSIMSS ASENSTEPWF CDACKCGVAP SCELCPNQDG IFKETDAGSN RWVHVVCALY
VPGVAFGDID KLRPVTLTEM NYSKYGAKKQ ECSFCEDPRF ARTGVCISCD AGMCRAYFHV
TCAQREGLLL MERKAKQDIA DPFFAYCKQH ADRFDRKWKR KNYLALQSYC KMSLQEREKQ
LSPEAQARIT ARLQQYRAKA ELARNTRPQA WVPREKLPRP LTSSASAIRK LMRKAELMGI
STDIFPVDTS DTSSSADGRR KHKQPALSAD FVNYYLERNM RMIQIQENIA EQKNIKDKLE
NEQEKLHIEY NKLCESLEDF QNLNSNLRNE GQAVWTVLGK ILGQKLNIPA ILRAPKERKP
SKKEGGTQKS SALPAVLYSC GICKKNHDQH LLLLCDTCKL HYHLGCLDPP LTRMPKKTKN
SYWQCSECDQ AGSSDIEADV AMETLPDGTK RSRRQIKEPV KFVPQDVPIE PKKVPIRNTR
TRGQKRKRSF IAEEEKSEER TPRERRQRLP APQKKPKLED LRTECATCRG PGDNENLVR
//
