ID H3AFQ3_LATCH Unreviewed; 190 AA.
AC H3AFQ3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Interleukin 17C {ECO:0008006|Google:ProtNLM};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000008474.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000008474.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-17 family.
CC {ECO:0000256|ARBA:ARBA00007236}.
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DR EMBL; AFYH01193564; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AFQ3; -.
DR STRING; 7897.ENSLACP00000008474; -.
DR Ensembl; ENSLACT00000008542.1; ENSLACP00000008474.1; ENSLACG00000007501.1.
DR eggNOG; ENOG502S2UJ; Eukaryota.
DR GeneTree; ENSGT00940000166375; -.
DR HOGENOM; CLU_121730_0_0_1; -.
DR InParanoid; H3AFQ3; -.
DR OMA; FAFHAEF; -.
DR TreeFam; TF314701; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020440; IL-17_chr.
DR InterPro; IPR010345; IL-17_fam.
DR Pfam; PF06083; IL17; 1.
DR PRINTS; PR01932; INTRLEUKIN17.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..190
FT /note="Interleukin 17C"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003579544"
SQ SEQUENCE 190 AA; 22292 MW; 1E88982D1CB66912 CRC64;
FYVFFLFCWQ VAVLLCFCFC LAQGRRHKSS KEDDCFPMNE VEGNEKLVHH FVGKHVRWDR
YPSVFLVQQL EENESDSRRK RRHHRHGCPV LRLQNVSASD YSQRSISPWR YRIDFDENRY
PQKLAFAECL CSGCINVSTG KETSSMNSVV IEQTMMVLFR RPCAKNPKAY SFEVDYIKVP
VGCTCVLPKM
//
