ID H3AGZ6_LATCH Unreviewed; 2955 AA.
AC H3AGZ6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 10-FEB-2021, entry version 38.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000008917};
GN Name=CENPF {ECO:0000313|Ensembl:ENSLACP00000008917};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000008917, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Ensembl:ENSLACP00000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Ensembl:ENSLACP00000008917};
RX PubMed=9215903;
RA Zardoya R., Meyer A.;
RT "The complete DNA sequence of the mitochondrial genome of a 'living
RT fossil,' the coelacanth (Latimeria chalumnae).";
RL Genetics 146:995-1010(1997).
RN [2] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSLACP00000008917}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
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DR EMBL; AFYH01094288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01094289; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01094290; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01094291; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01094292; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01094293; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01094294; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01094295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSLACT00000008986; ENSLACP00000008917; ENSLACG00000007875.
DR GeneTree; ENSGT00730000111187; -.
DR HOGENOM; CLU_000551_0_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 1..305
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1901..2041
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2137..2276
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2807..2849
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 205..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1697..1716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2663..2688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2722..2776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2897..2955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 20..82
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 97..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 162..189
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 285..400
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 405..520
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 532..594
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 605..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 654..709
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 714..741
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 781..801
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 813..889
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 900..920
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 928..955
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 963..997
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1005..1110
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1125..1203
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1211..1270
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1298..1339
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1347..1367
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1375..1395
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1436..1463
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1487..1556
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1568..1620
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1849..1883
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1898..1946
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1954..2005
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2010..2051
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2148..2252
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2264..2291
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2299..2319
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2334..2354
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2362..2403
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2411..2473
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2478..2552
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2567..2623
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2631..2658
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2702..2722
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 205..238
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..278
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2722..2759
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2760..2776
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2897..2933
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2955 AA; 342120 MW; A2E473081652BAB6 CRC64;
MSWAIEEWKE GLPSKALQKI QDFESQLEKL KKERQQKQFQ LESLEAAFQK QKQKVENEKS
EVTALKRENQ SLVESCDNLE KSKQKISHDL QVKELQVNFL EGQLATCKKQ IEKLEQEMKR
SKCEIERSQQ PLLLGDLQPC ATPEKNFAVP VAPSRNYNDS KVEELQEKYN KEVEERKRLE
AELKIMQAKV VNQSQGNVNR RDIARQQASS SVFPWQQEQT PSHAASNSLE TPSRRGCTTS
HFPWEREETP SMYCQRSAKK TASNSSFNES SSNSPQNDLL KVQNQEELNS KVTELELRLQ
AQEKEMKTCA NKLQEVQAHF EKAKLELSEK DKALNKYRDE VTKMTTQLDQ SSSKCEVVEQ
KLKQVSEELI CQRQNTDSAR HTMEQRLKEK EKEYQQELCQ QLHSFQILDQ QFKQMKTELQ
QAKNDRNTLQ AEIDKLSTMK QRAEKEVEDM KQTLFRTEQT LQAKEKDFKK TVEEVQKEKN
NLHCQFEQSS RQVHQQEEEL KMTQQHLKQS QSLVEELKSK NIAREVQLLS FKEKLDKQEQ
SLNTDLENLR QTVADLQKQQ DSAQDILTKR EKEMEEMNNK IITMEKETEE LQNALCLKYN
ECAELKRETS LLSEWKNKTE NLKNQMLCEK EGMLKEIQEL EKCLESHQYD NERIKVLENE
KQNLCLQIEN YERLLDCKSA DLESQKQIYE KLRKTAEQAD QKYSKEKENM CLQVIQLTAQ
ANGLEKKLQL ETNKILKMEQ SYSELCAEYE RATNLAKSKE SVIELKEAEM LNLQNSLSET
IIDFEKQLAK VNSEKSDLIK EHENAVLGKA VEAENMKLEL EKCQNDIAFS KEQISSLECD
LKLQKDLNSE LESRCEELMK VKDELEEKLV EVAKNLEIVQ AEAKEERELK ITVSAQQQRV
DDLLATVQEK EMSIQKLTSE QERKESCLQS LQSSNQLLEV QVQQLNIQSE AQRQEKEDIL
ASIFSNEKEV ENLAKENEKL KEVIDTLSQE KQVLLEKNSN FANMVKEKEA EVSELSTRRA
EEHQTILENN VKLESELANL QKKYSCMEET KDELEVQIKE KTEKLEEQER KFNKQCAEYL
SKMEHYEEAN QSLVKEVEKV QSSLNNKLEE TTQFKERLIV SEKETENLRK KLSDTTEGYK
ELQEMLRRLQ QENELLNQQN QQLKSSELAK EKTQYGEELR EAMREKESDL SKIQVQLEML
QMDLEDKEVC IESYSTQIEQ MEATVKKMES ELRESEEQKT IVREEKNSLC KELEATKSKL
SDALEKEQIL KLCAEHKEQS EKELAAVSQE YKSCQLLKTK LETSLQEVSS KCEELEKMYE
RMQTEKSELI SELSNLRTQC TTVLDENSGL ADKIKHLENE VNLSKDESTA LHSKLMSLKD
ENEKLKEWAK QEECEKLKLC NKEIERHLFE VNEKLSCSQK EYDIVQEQYC CAMSKVSELQ
SLVETLEEEK SVLVAKLEES AEVDKADELQ TQLNMAERKL FDTEIILSKT NVEKAALEAE
VNILETSLES AQLQLTEQKA QLQHLEQLIL ERETEVMDLK EQLNDFKGNL VSKENNASQT
EGNLPKEIEE LKILSETYET GIKKLEEQLQ MQKDARNGEI QELSQTLAAT KNELTCLQKQ
HSSEIDQWQQ KLSSMTLEME TKLAAERQQT EILSTELKGA RIQIQHLDLS SHSLLCAETE
EDQKEEINEN LQYINSFSKD PQSEPQSNER DGIETENTID ISQENISRLD VETETDSVAD
NTVECLRATV EFLCLDSNTS THQEDFQETH VVPESCTSQP ENVSSKQEFL SQELEEYKKD
DILLKEEQHL YSRLDSQQLQ STSQNSACTE LQNVVYKLEE EKSVLSDRIK STNLENQKLS
ERIKDLEKEL NSMTSEQEVY KARLSDVTEM LHSLEMVKGN WNEKYLEVEN ELKRTRSEKA
NLEKHILSME ADIEEMQIAK TSLEKEAANS SKCISRLGEQ LSVATADKNQ LSQELESSRE
IQEELEQISQ NLKEKLEQLA SDKVNYTEFI KVLEAENKKL TKQLEITKFD VEKLSKERNS
ILEQLDCLEK NVLSDEKGEL QKQFDQRTEE KEVLLNECET LQGKICALEM ENSRLSQSLE
SSLVEKGEIA SRLNSTQEEV VQMRHGIEKL KVRIESDEKK RHHEAEKLKA SERKADSFQD
KVEKLQRELQ MSEESLEGMV LEAETVKEEM EKLVTVKQEI SKKLQILETE VNTLSSERDL
LDKELQQKQL KISELEGSCM DITNLLKKVE EEKLQVMQEH VVSQKALKSE LMELNEKLKI
CSEELENWRA KEQDWLGQIS GLECEKTELS QQLQQKESSF AELHSANVSL TQDLLASKQE
LNEQVKANNR LQQEVTDMQQ WKQKISEQLS NVEAEKVSLE KERNQLQTIT TESEQRVQAL
EAKNFKMQGT IEGLEGSQQL LEDELQSAKL QNSALLEQIQ KITENDSRVR SDLNAANQKI
EKMQEECNLE RSTLVAQINN AQQQEESYKV QLDLVTSEKE EMKKRLQHLQ NELQISEEKI
KEERMEYQHQ LQEAEEKQKT LLKEGREKYE AEVHTEREKL ITMRQMLNDH ILEINNLKSA
KEQLNAALRK AESKLEQLNE KKVEDLKTTI VQLKKEKESA VSKLQLWMRS CKQMEQEKEM
LLKDIEQQDA LLNKLKKNEK IETDTNADGV SSELEELRET VEEKTREADE SMEKYCNLII
NYHKLEEANE TLKNRIAFLS SQLKQPGSQD SNSTAKTTPD NPPNSKTGNL KTGKTSPWDR
SRPCNKRHRT VEPKEDGLEL EKVEATECVS KRIRNGKENG MSRHSAGGDN VEFKPEGLPE
VVKKGFADIP AGTASPFILR RTTLQRRSPR LAAQKTSPIT QVVQKVALEN QAQNSKTPGG
SKLQQVKEVS SFSLGSVLGP VASTSGSPLS SVINSPKKTA FQIPSGSAPT RRSRRSPSTR
KYPEQEEEEE NCNVQ
//
