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Database: UniProt
Entry: H3AGZ6_LATCH
LinkDB: H3AGZ6_LATCH
Original site: H3AGZ6_LATCH 
ID   H3AGZ6_LATCH            Unreviewed;      2955 AA.
AC   H3AGZ6;
DT   18-APR-2012, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 1.
DT   10-FEB-2021, entry version 38.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSLACP00000008917};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSLACP00000008917};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000008917, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Ensembl:ENSLACP00000008917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Ensembl:ENSLACP00000008917};
RX   PubMed=9215903;
RA   Zardoya R., Meyer A.;
RT   "The complete DNA sequence of the mitochondrial genome of a 'living
RT   fossil,' the coelacanth (Latimeria chalumnae).";
RL   Genetics 146:995-1010(1997).
RN   [2] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSLACP00000008917}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AFYH01094288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01094289; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01094290; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01094291; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01094292; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01094293; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01094294; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01094295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSLACT00000008986; ENSLACP00000008917; ENSLACG00000007875.
DR   GeneTree; ENSGT00730000111187; -.
DR   HOGENOM; CLU_000551_0_0_1; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   DOMAIN          1..305
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1901..2041
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2137..2276
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2807..2849
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          205..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1697..1716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2663..2688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2722..2776
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2897..2955
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..82
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          97..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          162..189
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          285..400
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          405..520
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          532..594
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          605..625
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          654..709
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          714..741
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          781..801
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          813..889
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          900..920
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          928..955
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          963..997
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1005..1110
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1125..1203
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1211..1270
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1298..1339
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1347..1367
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1375..1395
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1436..1463
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1487..1556
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1568..1620
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1849..1883
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1898..1946
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1954..2005
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2010..2051
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2148..2252
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2264..2291
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2299..2319
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2334..2354
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2362..2403
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2411..2473
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2478..2552
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2567..2623
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2631..2658
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2702..2722
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        205..238
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..278
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2722..2759
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2760..2776
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2897..2933
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2955 AA;  342120 MW;  A2E473081652BAB6 CRC64;
     MSWAIEEWKE GLPSKALQKI QDFESQLEKL KKERQQKQFQ LESLEAAFQK QKQKVENEKS
     EVTALKRENQ SLVESCDNLE KSKQKISHDL QVKELQVNFL EGQLATCKKQ IEKLEQEMKR
     SKCEIERSQQ PLLLGDLQPC ATPEKNFAVP VAPSRNYNDS KVEELQEKYN KEVEERKRLE
     AELKIMQAKV VNQSQGNVNR RDIARQQASS SVFPWQQEQT PSHAASNSLE TPSRRGCTTS
     HFPWEREETP SMYCQRSAKK TASNSSFNES SSNSPQNDLL KVQNQEELNS KVTELELRLQ
     AQEKEMKTCA NKLQEVQAHF EKAKLELSEK DKALNKYRDE VTKMTTQLDQ SSSKCEVVEQ
     KLKQVSEELI CQRQNTDSAR HTMEQRLKEK EKEYQQELCQ QLHSFQILDQ QFKQMKTELQ
     QAKNDRNTLQ AEIDKLSTMK QRAEKEVEDM KQTLFRTEQT LQAKEKDFKK TVEEVQKEKN
     NLHCQFEQSS RQVHQQEEEL KMTQQHLKQS QSLVEELKSK NIAREVQLLS FKEKLDKQEQ
     SLNTDLENLR QTVADLQKQQ DSAQDILTKR EKEMEEMNNK IITMEKETEE LQNALCLKYN
     ECAELKRETS LLSEWKNKTE NLKNQMLCEK EGMLKEIQEL EKCLESHQYD NERIKVLENE
     KQNLCLQIEN YERLLDCKSA DLESQKQIYE KLRKTAEQAD QKYSKEKENM CLQVIQLTAQ
     ANGLEKKLQL ETNKILKMEQ SYSELCAEYE RATNLAKSKE SVIELKEAEM LNLQNSLSET
     IIDFEKQLAK VNSEKSDLIK EHENAVLGKA VEAENMKLEL EKCQNDIAFS KEQISSLECD
     LKLQKDLNSE LESRCEELMK VKDELEEKLV EVAKNLEIVQ AEAKEERELK ITVSAQQQRV
     DDLLATVQEK EMSIQKLTSE QERKESCLQS LQSSNQLLEV QVQQLNIQSE AQRQEKEDIL
     ASIFSNEKEV ENLAKENEKL KEVIDTLSQE KQVLLEKNSN FANMVKEKEA EVSELSTRRA
     EEHQTILENN VKLESELANL QKKYSCMEET KDELEVQIKE KTEKLEEQER KFNKQCAEYL
     SKMEHYEEAN QSLVKEVEKV QSSLNNKLEE TTQFKERLIV SEKETENLRK KLSDTTEGYK
     ELQEMLRRLQ QENELLNQQN QQLKSSELAK EKTQYGEELR EAMREKESDL SKIQVQLEML
     QMDLEDKEVC IESYSTQIEQ MEATVKKMES ELRESEEQKT IVREEKNSLC KELEATKSKL
     SDALEKEQIL KLCAEHKEQS EKELAAVSQE YKSCQLLKTK LETSLQEVSS KCEELEKMYE
     RMQTEKSELI SELSNLRTQC TTVLDENSGL ADKIKHLENE VNLSKDESTA LHSKLMSLKD
     ENEKLKEWAK QEECEKLKLC NKEIERHLFE VNEKLSCSQK EYDIVQEQYC CAMSKVSELQ
     SLVETLEEEK SVLVAKLEES AEVDKADELQ TQLNMAERKL FDTEIILSKT NVEKAALEAE
     VNILETSLES AQLQLTEQKA QLQHLEQLIL ERETEVMDLK EQLNDFKGNL VSKENNASQT
     EGNLPKEIEE LKILSETYET GIKKLEEQLQ MQKDARNGEI QELSQTLAAT KNELTCLQKQ
     HSSEIDQWQQ KLSSMTLEME TKLAAERQQT EILSTELKGA RIQIQHLDLS SHSLLCAETE
     EDQKEEINEN LQYINSFSKD PQSEPQSNER DGIETENTID ISQENISRLD VETETDSVAD
     NTVECLRATV EFLCLDSNTS THQEDFQETH VVPESCTSQP ENVSSKQEFL SQELEEYKKD
     DILLKEEQHL YSRLDSQQLQ STSQNSACTE LQNVVYKLEE EKSVLSDRIK STNLENQKLS
     ERIKDLEKEL NSMTSEQEVY KARLSDVTEM LHSLEMVKGN WNEKYLEVEN ELKRTRSEKA
     NLEKHILSME ADIEEMQIAK TSLEKEAANS SKCISRLGEQ LSVATADKNQ LSQELESSRE
     IQEELEQISQ NLKEKLEQLA SDKVNYTEFI KVLEAENKKL TKQLEITKFD VEKLSKERNS
     ILEQLDCLEK NVLSDEKGEL QKQFDQRTEE KEVLLNECET LQGKICALEM ENSRLSQSLE
     SSLVEKGEIA SRLNSTQEEV VQMRHGIEKL KVRIESDEKK RHHEAEKLKA SERKADSFQD
     KVEKLQRELQ MSEESLEGMV LEAETVKEEM EKLVTVKQEI SKKLQILETE VNTLSSERDL
     LDKELQQKQL KISELEGSCM DITNLLKKVE EEKLQVMQEH VVSQKALKSE LMELNEKLKI
     CSEELENWRA KEQDWLGQIS GLECEKTELS QQLQQKESSF AELHSANVSL TQDLLASKQE
     LNEQVKANNR LQQEVTDMQQ WKQKISEQLS NVEAEKVSLE KERNQLQTIT TESEQRVQAL
     EAKNFKMQGT IEGLEGSQQL LEDELQSAKL QNSALLEQIQ KITENDSRVR SDLNAANQKI
     EKMQEECNLE RSTLVAQINN AQQQEESYKV QLDLVTSEKE EMKKRLQHLQ NELQISEEKI
     KEERMEYQHQ LQEAEEKQKT LLKEGREKYE AEVHTEREKL ITMRQMLNDH ILEINNLKSA
     KEQLNAALRK AESKLEQLNE KKVEDLKTTI VQLKKEKESA VSKLQLWMRS CKQMEQEKEM
     LLKDIEQQDA LLNKLKKNEK IETDTNADGV SSELEELRET VEEKTREADE SMEKYCNLII
     NYHKLEEANE TLKNRIAFLS SQLKQPGSQD SNSTAKTTPD NPPNSKTGNL KTGKTSPWDR
     SRPCNKRHRT VEPKEDGLEL EKVEATECVS KRIRNGKENG MSRHSAGGDN VEFKPEGLPE
     VVKKGFADIP AGTASPFILR RTTLQRRSPR LAAQKTSPIT QVVQKVALEN QAQNSKTPGG
     SKLQQVKEVS SFSLGSVLGP VASTSGSPLS SVINSPKKTA FQIPSGSAPT RRSRRSPSTR
     KYPEQEEEEE NCNVQ
//
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