ID H3AI63_LATCH Unreviewed; 324 AA.
AC H3AI63;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=CYFIP related Rac1 interactor B {ECO:0000313|Ensembl:ENSLACP00000009334.1};
GN Name=CYRIB {ECO:0000313|Ensembl:ENSLACP00000009334.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000009334.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000009334.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CYRI family.
CC {ECO:0000256|ARBA:ARBA00005778}.
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DR EMBL; AFYH01041176; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041177; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041179; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041180; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041181; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041182; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041183; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041184; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01041185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AI63; -.
DR STRING; 7897.ENSLACP00000009334; -.
DR Ensembl; ENSLACT00000009405.1; ENSLACP00000009334.1; ENSLACG00000008235.1.
DR eggNOG; KOG3951; Eukaryota.
DR GeneTree; ENSGT00390000015159; -.
DR HOGENOM; CLU_056470_0_0_1; -.
DR InParanoid; H3AI63; -.
DR OMA; EYRSRFN; -.
DR TreeFam; TF314541; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000008235; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR InterPro; IPR039789; CYRI.
DR InterPro; IPR009828; CYRIA/CYRIB_Rac1-bd.
DR PANTHER; PTHR12422:SF3; CYFIP-RELATED RAC1 INTERACTOR B; 1.
DR PANTHER; PTHR12422; UNCHARACTERIZED; 1.
DR Pfam; PF07159; CYRIA-B_Rac1-bd; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 18..320
FT /note="CYRIA/CYRIB Rac1 binding"
FT /evidence="ECO:0000259|Pfam:PF07159"
SQ SEQUENCE 324 AA; 36871 MW; F58B491E92DF7C6B CRC64;
MGNLLKVLTC TDLEQGPNFF LDFENAQPTD SEREIYNQVD IVLKDAEGIL DDLQSYRGAG
HEIREAIQNP SDEKLQEKAW GAVVPLVGKL KKFYEFSQRL EAALHGLLGA LTSTPYTPTQ
HLEREQALAK QFAEILHFTL RFDELKMTNP AIQNDFSYYR RTLSRMRINN VPVTRHETFL
MGLNNRNTFP DVQSTKLLQS QFLMNGILLS ENKSLPIENT TDCLSTMASV CKVMLETPEY
RSRFANEDTV SFCLRVMVGV IILYDHVHPV GAFAKTSKFD MKGCIKVLKD QPPNSVEGLL
NALRYTTKHL NDESTSKQIR SMLQ
//
