ID H3AIB2_LATCH Unreviewed; 469 AA.
AC H3AIB2;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=PHD finger protein 10 {ECO:0000256|ARBA:ARBA00016995};
GN Name=PHF10 {ECO:0000313|Ensembl:ENSLACP00000009383.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000009383.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000009383.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SAYP family.
CC {ECO:0000256|ARBA:ARBA00006097}.
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DR EMBL; AFYH01115148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01115149; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01115150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AIB2; -.
DR Ensembl; ENSLACT00000009454.1; ENSLACP00000009383.1; ENSLACG00000008276.1.
DR GeneTree; ENSGT00940000155172; -.
DR HOGENOM; CLU_028634_2_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000008276; Expressed in pelvic fin and 5 other cell types or tissues.
DR GO; GO:0071564; C:npBAF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd15528; PHD1_PHF10; 1.
DR CDD; cd15529; PHD2_PHF10; 1.
DR CDD; cd21085; WH_NTD_PHF10; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038045; PHF10_PHD_finger_1.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR PANTHER; PTHR45888:SF8; PHD FINGER PROTEIN 10; 1.
DR Pfam; PF00628; PHD; 2.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 348..407
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 404..452
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 469 AA; 53260 MW; 3498ADF2004BDD7C CRC64;
SFQDETEENS NDGSQAPKRR RMGSGDSSRS CDTTNQDFGS AYFPAENLIE YKWPPDEAGE
YYMLQEQVSE YLGVTSFKRK YPDLERRDLS HKEKLYLREL NVITETQCTL GLTALRSDEV
IDLMIKEYPT KHAEYSVILQ ERERQQITDR YKEYSQMQQQ NTQKVEPSKV PEYIKKAAKK
AAEFNSNLNR ERMEERRAYF DLQTHVIQVP QGKYKVLSPE RTKTGPYPVA LIPGQFQDYF
KKYSPNELRY LPLNTALYEP PLDPELPALD SDGDSDDAEE SKEKKTKGSS GSSSGNTSEG
DTPTENQEDS SHGKQKSRDR VSTLGKDGSK RTVPPKSVPG YKPKVIPNAI CGICLNGKES
NKKGKPEALI HCSQCHNSGH PSCLDMSVEL VSVIKTYPWQ CMECKTCIIC GQPHHEEEMM
FCDECDRGYH TFCVGLKVIP SGRWICECCI NDPTTPKKGI RRGKNSKEG
//
