ID H3AIQ3_LATCH Unreviewed; 434 AA.
AC H3AIQ3;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=ST18 C2H2C-type zinc finger transcription factor {ECO:0000313|Ensembl:ENSLACP00000009524.1};
GN Name=ST18 {ECO:0000313|Ensembl:ENSLACP00000009524.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000009524.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000009524.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MYT1 family.
CC {ECO:0000256|ARBA:ARBA00010194}.
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DR EMBL; AFYH01079196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079199; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079200; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079201; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079202; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079203; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079204; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01079205; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AIQ3; -.
DR Ensembl; ENSLACT00000009596.1; ENSLACP00000009524.1; ENSLACG00000008399.2.
DR GeneTree; ENSGT00940000159905; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.320.30; -; 2.
DR InterPro; IPR013681; Myelin_TF.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR PANTHER; PTHR10816:SF9; SUPPRESSION OF TUMORIGENICITY 18 PROTEIN; 1.
DR Pfam; PF08474; MYT1; 2.
DR Pfam; PF01530; zf-C2HC; 2.
DR SUPFAM; SSF103637; CCHHC domain; 2.
DR PROSITE; PS51802; ZF_CCHHC; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01143}.
FT DOMAIN 200..252
FT /note="Myelin transcription factor 1"
FT /evidence="ECO:0000259|Pfam:PF08474"
FT DOMAIN 261..426
FT /note="Myelin transcription factor 1"
FT /evidence="ECO:0000259|Pfam:PF08474"
FT REGION 319..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 434 AA; 48129 MW; CEF4063E1E9751D4 CRC64;
ATEESVEIDL SKGNLTLLEQ AITLQAEQGR VFHSAYKQFD RFLLEQLAEE RRHCKVTDPA
VGMSYNNHRD ASRSEKKETK CPTPGCDGTG HVTGLYPHHR SLSGCPHKIR VPPEILAMHE
NVLKCPTPGC TGRGHVNSNR STHRSLSGCP IAAAEKLTKS QERHLIDVAK TGLRTTEHSQ
DNKKPPTCLI KQFDISQANY RLAQPVTVAR ASLSKEQEKL WKAPFDYASF DAQVFGKRTA
APAVQERDTP QHVEFRFCCT GYSHNAEDAH MAAAAILNLS TRCKEAPENL STKPQDLSKN
TTIEVDENGT LDLSMKKNRN QDQATPVTTI SSSVSASDSS PIKPSSILVT AAFYQALCEQ
EGWDMPINYS KTNMKKDESK EQLKTSALVF SEIYKEEAES TAENLEERKY AGDVATPSPK
TKLPSRDLKK ELIT
//
