ID H3ALJ6_LATCH Unreviewed; 431 AA.
AC H3ALJ6;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Protein ABHD8 {ECO:0000256|ARBA:ARBA00039466};
DE AltName: Full=Alpha/beta hydrolase domain-containing protein 8 {ECO:0000256|ARBA:ARBA00041848};
GN Name=ABHD8 {ECO:0000313|Ensembl:ENSLACP00000010517.2};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000010517.2, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000010517.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily.
CC {ECO:0000256|ARBA:ARBA00008645}.
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DR EMBL; AFYH01122491; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006001689.1; XM_006001627.2.
DR AlphaFoldDB; H3ALJ6; -.
DR STRING; 7897.ENSLACP00000010517; -.
DR ESTHER; latch-h3alj6; ABHD8.
DR MEROPS; S33.011; -.
DR Ensembl; ENSLACT00000010596.2; ENSLACP00000010517.2; ENSLACG00000009266.2.
DR GeneID; 102361619; -.
DR KEGG; lcm:102361619; -.
DR CTD; 101883400; -.
DR eggNOG; KOG2382; Eukaryota.
DR GeneTree; ENSGT00390000007336; -.
DR HOGENOM; CLU_057347_0_0_1; -.
DR InParanoid; H3ALJ6; -.
DR OMA; VHCQRRI; -.
DR OrthoDB; 3044577at2759; -.
DR TreeFam; TF331708; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR000639; Epox_hydrolase-like.
DR PANTHER; PTHR42886:SF93; PROTEIN ABHD8; 1.
DR PANTHER; PTHR42886; RE40534P-RELATED; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PRINTS; PR00111; ABHYDROLASE.
DR PRINTS; PR00412; EPOXHYDRLASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 171..273
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 127..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 47726 MW; D8CB4BC226C45C00 CRC64;
MLNTITDGIL CCLTGKGDNS VGPIESVESS DGYDYVEVKP GRVLRVKHIV PTSTATKSAV
EEQQPSEKGI VHCKRKITVY RNGQLVIENL GDVIRSELLH CQNGNTEANN TVELELSDFA
STSTAYNGNN PTAAAREAGT GRRRKRKPKK SVVIDCKKKI TSCKGTHSDV ALFFIHGVGG
SLDIWKEQLD FFSKLGYEVV APDLAGHGSS SAPQIAAAYT FYALAEDMRS IFKRYAKKRN
ILIGHSYGVS FCTFLAHEYP DQVHKVVMVN GGGPTALEPS LCSIFNLPTC VLHCLSPCLA
WSFLKAGFAR QGAKEKQLLK EGNAFNVSSF VLRAMMSGQY WPEGDEVYHA ELTVPMLLVH
GMHDKFVPVE EDQRMAEILL IAFLKIIEEG SHMVMMECPE TVNTLLHEFF LWEPEVTLKE
VQETEEKTQS K
//
