ID H3ALX1_LATCH Unreviewed; 519 AA.
AC H3ALX1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=LRR binding FLII interacting protein 1 {ECO:0000313|Ensembl:ENSLACP00000010642.1};
GN Name=LRRFIP1 {ECO:0000313|Ensembl:ENSLACP00000010642.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000010642.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000010642.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LRRFIP family.
CC {ECO:0000256|ARBA:ARBA00008275}.
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DR EMBL; AFYH01083861; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083862; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083863; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083864; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083865; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083867; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083869; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01083870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3ALX1; -.
DR STRING; 7897.ENSLACP00000010642; -.
DR Ensembl; ENSLACT00000010721.1; ENSLACP00000010642.1; ENSLACG00000009375.1.
DR eggNOG; KOG2010; Eukaryota.
DR GeneTree; ENSGT00530000063564; -.
DR InParanoid; H3ALX1; -.
DR OMA; PHAWTNG; -.
DR TreeFam; TF314109; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000009375; Expressed in chordate pharynx and 6 other cell types or tissues.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.5.4090; -; 1.
DR InterPro; IPR019139; LRRFIP1/2.
DR PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR PANTHER; PTHR19212:SF5; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 1; 1.
DR Pfam; PF09738; LRRFIP; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 171..278
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 369..511
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 90..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 519 AA; 59851 MW; 6FAF0FAEC8E6853D CRC64;
MEMGSQGPGR RRVPNRERLS AEDDALNQIA REAEARLAAK RAARAEAREI RMKELERQQK
EIYQVQKKYY GLDTKFGDIE QWMEDSERFS RRTRRYTSAS DEDERMSVGS RGSLRSDLEC
AGAYGRAGFG KEKAKLRSSK AGTHYSDLAH YSSGLSSKSH SSSLNGNRDS LAEVEEKYRK
AMVSNAQLDN EKTNLMYQVD TLKDALVELE EHLAETRRDY EEKCKEFERQ KHAYSILQFQ
FNEIKESLQQ REEMLTEIRQ LQQKQESFIR EISDLQETIE WKDKKIGALE RQKEFFDTIR
SERDELRDEV TILRDTMKSH GIVLGMEVTT NGEIMEGLTD GEADSESRVP QETSQALPAT
GDRLPDIKVK KLIEERESLL EQIKELKANL DDKQKSVKME KSTAEDEVLE NGTDAHVMDL
QRDANRQISD LKFKLVKAEQ EITALEQNAI RLEGQVLRYK GAAESAEKVE DELKAEKRKL
QRELRTALDK VEELEVSNSH LTKRLEKMKA IRSAILAQQ
//
