ID H3AMF0_LATCH Unreviewed; 398 AA.
AC H3AMF0;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=ETS variant transcription factor 1 {ECO:0000313|Ensembl:ENSLACP00000010821.1};
GN Name=ETV1 {ECO:0000313|Ensembl:ENSLACP00000010821.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000010821.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000010821.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR EMBL; AFYH01099039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099041; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01099042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H3AMF0; -.
DR STRING; 7897.ENSLACP00000010821; -.
DR Ensembl; ENSLACT00000010901.1; ENSLACP00000010821.1; ENSLACG00000009525.1.
DR eggNOG; KOG3806; Eukaryota.
DR GeneTree; ENSGT00940000157123; -.
DR HOGENOM; CLU_030025_0_0_1; -.
DR InParanoid; H3AMF0; -.
DR OMA; DYQAESX; -.
DR TreeFam; TF316214; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000009525; Expressed in post-anal tail muscle and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR006715; ETS_PEA3_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF196; ETS TRANSLOCATION VARIANT 1; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF04621; ETS_PEA3_N; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 256..336
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 56..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 398 AA; 45966 MW; 2101CB036AA8DF79 CRC64;
SFFSPVAFHG LPLKIKKEPQ SPCSELNSAC SQEQPFKFSY GEKCLYNVSA YDQKPQVGMK
ASSPPTPSST PVSPLHHASP KPDRSFPTHL PPSQPIPDNN YPMDHRFRRQ LSEPCNSFPP
LPAIPNEGRP MYQRQMSEPS IPFPPQGFKQ EYHDPVYEHA AMVRGPANQN FPPPMMIKQE
PRDFTYDSEV PSCHSIYMRQ DGFLAHANRN EGCMYEKGPR HFFDDTCVVP EKFEGDIKQE
PGMYREGPTY QRRGSLQLWQ FLVALLDDPS NSHFIAWTGR GMEFKLIEPE EVARRWGIQK
NRPAMNYDKL SRSLRYYYEK GIMQKVAGER YVYKFVCDPE ALFSMAFPDN QRPLLKADLE
RHINEEDTIP LSHFDESMAY MQEGGYCNTQ PYNEGYVY
//
