ID H3ANG1_LATCH Unreviewed; 199 AA.
AC H3ANG1;
DT 18-APR-2012, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Protein RER1 {ECO:0000256|ARBA:ARBA00014112, ECO:0000256|PIRNR:PIRNR016013};
GN Name=LOC102348004 {ECO:0000313|Ensembl:ENSLACP00000011182.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000011182.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000011182.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in the retrieval of endoplasmic reticulum membrane
CC proteins from the early Golgi compartment.
CC {ECO:0000256|ARBA:ARBA00003348, ECO:0000256|PIRNR:PIRNR016013}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the RER1 family. {ECO:0000256|ARBA:ARBA00006070,
CC ECO:0000256|PIRNR:PIRNR016013}.
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DR EMBL; AFYH01172313; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01172314; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006006543.1; XM_006006481.2.
DR AlphaFoldDB; H3ANG1; -.
DR STRING; 7897.ENSLACP00000011182; -.
DR Ensembl; ENSLACT00000011266.1; ENSLACP00000011182.1; ENSLACG00000009839.1.
DR GeneID; 102348004; -.
DR eggNOG; KOG1688; Eukaryota.
DR GeneTree; ENSGT00510000047137; -.
DR HOGENOM; CLU_074889_1_0_1; -.
DR InParanoid; H3ANG1; -.
DR OMA; FFITMKR; -.
DR OrthoDB; 415184at2759; -.
DR TreeFam; TF300029; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000009839; Expressed in muscle tissue and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR InterPro; IPR004932; Rer1.
DR PANTHER; PTHR10743; PROTEIN RER1; 1.
DR PANTHER; PTHR10743:SF0; PROTEIN RER1; 1.
DR Pfam; PF03248; Rer1; 1.
DR PIRSF; PIRSF016013; AtER_Rer1p; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR016013};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 199 AA; 23085 MW; 614F3E9BEB050A3B CRC64;
MSEGDGSSDS IHGTPSFISM FCTRVGQIYQ SLLDRATPHT TARWLVTLGL AVLYLLRVFL
LQGWYIVTYA LGIYHLNLFI AFLSPKVDPA VMEDSDDDED GPSLPTRQNE EFRPFIRRLP
EFKFWYSGTK AILVAMFCTC FEAFNVPVFW PILVMYFITL FCMTMKRQIK HMIRYRYLPF
TFGKKKYSGK EDTGQVFIS
//
